Evidence map›Paper›PMID 41195808›Full record

Trial reportInternational biomechanics2025

Stochastic resonance stimulation effect on stability during walking in people with Parkinson disease.

Eman Alsaqabi, Stephen DiBianca, Ashwini Sansare, Khushboo Verma, Hendrik Reimann, John Jeka

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International biomechanics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06829342 (The Role of Sensory Deficits in the Neural Control of Balance During Walking in Parkinson's Disease), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06829342 nacompletednot on this map

The Role of Sensory Deficits in the Neural Control of Balance During Walking in Parkinson's Disease

TypeinterventionalSponsorUniversity of DelawareRan2021 to 2022Enrolled21ConditionsParkinson DiseaseArmsStochastic Resonance (SR)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eman AlsaqabiDepartment of Physical Therapy, College of Allied Health Sciences, Kuwait University, Kuwait City, Kuwait.
Stephen DiBiancaDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
Ashwini SansareDepartment of Kinesiology and Sports Medicine, Texas A&M University, College Station, TX, USA.
Khushboo VermaDepartment of Physical Therapy, University of Delaware, Newark, DE.
Hendrik ReimannDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
John JekaDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People with Parkinson disease (PwPD) often face challenges with maintaining balance while walking, which can stem from sensory dysfunction. Studies have identified different biomechanical strategies that aid in preserving upright balance control. Stochastic resonance (SR) stimulation delivers sub-threshold electrical noise to enhance the detection capabilities of dysfunctional sensory systems. Yet, the effectiveness of SR in enhancing gait stability in PwPD is undetermined. The purpose of this study was to investigate the effects of SR on balance control during visually perturbed walking in PwPD (NCT06829342).Fourteen individuals with PD completed the study. We established individualized sensory thresholds for SR stimulation and identified the optimal SR intensity. Following this, the participants walked within a virtually perturbed environment. Center of mass (CoM) excursion, foot placement, and ankle roll responses were assessed bilaterally.Peak CoM excursion showed a significant increase, indicating reduced stability, with the SR condition compared to no-SR at the more affected side. Outcome measures related to balance control mechanisms were insignificant.With SR, PwPD were driven by the induced fall with more sway and without significant alterations in balance strategies, which might be due to adding more noise to sensory processing and misidentifying the more affected side.

Indexed as

Parkinson DiseasePostural BalanceWalkingAgedBiomechanical PhenomenaFemaleGaitHumansMaleMiddle AgedStochastic ProcessesElectric stimulation therapygaitParkinson diseasepostural controlsomatosensory deficitsstochastic resonance

Identifiers

PMID41195808
PMCPMC12599153

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.