ArticleJournal of the American Heart Association2025
Adhering to Life's Essential 8 Is Associated With Greater Bone Mineral Accrual During Childhood and Adolescence.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease and osteoporosis both originate from childhood and share several risk factors. However, the relationship between cardiovascular health (CVH) and bone mass remains unclear in children.
methodsData of 11 468 (50.7% male) Chinese children aged 6 to 18 were obtained from a nationwide cross-sectional survey during 2013 to 2019. CVH was assessed based on 8 metrics (4 behavioral metrics: diet, physical activity, nicotine exposure, sleep health; and 4 factor metrics: body mass index, blood lipids, blood glucose, blood pressure) according to Life's Essential 8 construct. Scores for CVH behavior and CVH factor were categorized as low (0-49), moderate (50-79), or high (80-100). Bone mineral content and bone mineral density for the total body less head and lumbar spine were measured using dual-energy X-ray absorptiometry.
resultsIn unadjusted models, subjects with high CVH behavior but low CVH factor scores showed higher level and greater growth rate of bone mass than their counterparts. After adjustment for covariates, subjects with high scores of CVH behavior or CVH factor demonstrated 0.165 to 0.427 higher
conclusionsHigh CVH, especially high CVH behaviors, is significantly associated with greater and faster accrual of childhood bone minerals. These results suggest that behavioral guidance for promoting optimal CVH may optimize bone mass accretion in early life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.