ArticleJournal of the American Heart Association2025
Vessel-Specific Myocardial Mass in Patients With Stable Coronary Artery Disease.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Evaluation of a Virtual Non-invasive Percutaneous Intervention Planner in Patients With Coronary Artery Disease.
Pullback Pressure Gradient (PPG) Global Registry: Prospective Evaluation of the Impact of the PPG Index on Clinical Decision Making and Outcomes
Precise Procedural and PCI Plan (P4) Randomized Clinical Trial Integration of Coronary Computed Tomography Angiography in the Catheterization Laboratory to Plan and Guide Coronary Percutaneous Procedures
Pressure Microcatheter vs Pressure Wire for Clinical Decision Making and PCI Optimization
European microCirculatory Resistance and Absolute Flow Team: The Euro-CRAFT Registry
Who cites it
4 citing papers in PubMed.
- Vessel-Specific Differences in Fractional Flow Reserve Among Intermediate Coronary Lesions.Journal of clinical medicine · 2026Article
- Editorial: Coronary physiology in the spotlight: advancing diagnosis and treatment in CAD and microvascular disease.Frontiers in cardiovascular medicine · 2026Article
- Quantification of Myocardial Mass by Cardiac Computed Tomography: A Tool for Preprocedural Planning of Coronary Revascularization.Journal of the American Heart Association · 2025Article
- How Different is Invasive Coronary Physiology in the Left Anterior Descending Artery?Methodist DeBakey cardiovascular journal · 2025Review
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Authors and funding
41 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssessing the myocardial mass at risk is essential in evaluating patients with coronary artery disease. This study aims to establish reference values for vessel-specific myocardial mass derived from coronary computed tomography angiography, providing a quantitative assessment of the myocardial mass subtended by each epicardial vessel.
methodsLeft ventricular (LV) and vessel-specific myocardial mass were calculated from coronary computed tomography angiography using the Voronoi method in patients with stable coronary artery disease. Myocardial mass was quantified for each epicardial coronary artery with a diameter >1.5 mm.
resultsWe included 948 patients with 9228 epicardial coronary artery branches. Mean age was 66±9 years. The cohort was predominantly male (77%); 66% had hypertension, and 22% had diabetes. Vessel-specific myocardial mass was calculated for 2767 main epicardial arteries (948 left anterior descending, 948 left circumflex, and 871 right coronary artery) and 6461 side branches (1888 diagonals, 1208 septals, 1422 obtuse marginals, 247 ramus intermedius, 850 right posterior descending, and 846 posterolateral branches). Median LV mass was 141 grams (interquartile range 118-166); women had smaller LV mass than men (106 [93-123] grams versus 150 [132-173] grams,
conclusionsThis study quantified the myocardial mass subtended by each major artery in the coronary circulation. Understanding the vessel-specific mass at risk has significant clinical implications for personalizing revascularization strategies. REGISTRATION: This is a retrospective analysis of 5 prospectively conducted trials (P3: NCT03782688; P4: NCT05253677; PPG Global: NCT04789317; Euro-CRAFT: NCT05805462; INSIGHTFUL-FFR: NCT05437900). No additional registration was required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.