Evidence map›Paper›PMID 41195630›Full record

ArticleNeurourology and urodynamics2026

Validation of a Wireless Catheter-Free Ambulatory Urodynamics Device in Women With Neurogenic Bladder.

Michael D Gross, Brendan T Frainey, Madison E Lyon, Kevin C Lewis, Mohamed Elazab, Hassaan A Bukhari, Tyler Tevis, Robert S Butler, Reilly Burhanna, Cole Smith and 4 more

Abstract readValidation Study
In one paragraph

Article in Neurourology and urodynamics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Michael D GrossGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-9936-7133
Brendan T FraineyGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-0371-7122
Madison E LyonGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Kevin C LewisGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Mohamed ElazabDepartment of Biomedical Engineering, Cleveland Clinic Research, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-6623-9813
Hassaan A BukhariDepartment of Biomedical Engineering, Cleveland Clinic Research, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-5976-0483
Tyler TevisAdvanced Platform Technology Center, Louis Stokes VA Medical Center, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0002-1830-9914
Robert S ButlerQuantitative Health Sciences Department, Cleveland Clinic, Cleveland, Ohio, USA.
Reilly BurhannaDepartment of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0002-4290-3382
Cole SmithDepartment of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0007-9846-5373
Howard B GoldmanGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Ly Hoang-RobertsGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-3624-2592
Margot S DamaserGlickman Urology Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-4743-9283
Steve J A MajerusAdvanced Platform Technology Center, Louis Stokes VA Medical Center, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-5057-0189

Funding

The UroMonitor: Innovative Technology to Improve Management of Bladder DysfunctionR56EB031042 · NIBIB · CLEVELAND CLINIC LERNER COM-CWRU · PI DAMASER, MARGOT S. · 2021 to 2021
$949k
NIBIB NIH HHS R56 EB031042RRD VA I50 RX001871RRD VA IK6 RX003843This study was supported in part by funds from the Research Program Committee of the Cleveland Clinic and the Department of Veterans Affairs.
6 · The paper itself

Abstract

aimsUrodynamics (UDS) is critical for patients with neurogenic bladder but remains artificial given retrograde filling and voiding around a catheter in an uncomfortable setting. We have developed a wireless device for catheter-free real-time measurement of intravesical pressure during natural filling. Women with neurogenic bladder secondary to multiple sclerosis (MS) may experience discomfort, detrusor overactivity, or inability to urinate while observed during UDS which might belie true voiding patterns. The aim of this study was to test the wireless device in women with neurogenic bladder due to MS.

methodsTen female participants with neurogenic bladder secondary to MS underwent standard UDS, after which the device was inserted and a second UDS study performed. Patients then ambulated with only the device in place for an additional void.

resultsThere were no significant differences in UDS results, pain or discomfort between the first and second cycle. The device captured 98% of UDS events, including 100% of detrusor overactivity. Post void residual volume after UDS (160 ± 179 mL [Range 0-454]) was significantly greater than after ambulation with the wireless device alone (19 ± 18 mL [Range 0-46]; p = 0.01), demonstrating greater voiding efficiency with the wireless device alone than with the UDS catheter in place.

conclusionsThe device was well tolerated without complications, captured urodynamic data with a high degree of fidelity, and demonstrated additional utility in patients with borderline obstruction or inability to urinate while observed who cannot void during standard UDS. This device offers a promising alternative to the critical information provided by UDS in a less-invasive, more physiologic manner.

Indexed as

Urinary BladderUrinary Bladder, NeurogenicUrodynamicsWireless TechnologyAdultEquipment DesignFemaleHumansMiddle AgedMultiple SclerosisUrinary Bladder, OveractiveUrinationambulatory urodynamicsfemalemultiple sclerosistelemetric ambulatory urodynamic monitoringurodynamics

Identifiers

PMID41195630
PMCPMC13482406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.