Evidence map›Paper›PMID 41195577›Full record

ReviewCancer reports (Hoboken, N.J.)2025

Precision Diagnosis and Individualized Therapy of Non-Gestational Choriocarcinoma Invading the Corpus Uteri and Cervix: A Case Report and Literature Review.

Jiahui Ma, Fenghua Ma, Tingting Chen, Xin Lu, Yan Du, Xiaoni Yue

Abstract readCase ReportsReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahui MaClinical Research Unit, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.ORCID 0009-0003-8580-6109
Fenghua MaShanghai Key Lab of Reproduction and Development, Shanghai, China.ORCID 0000-0002-6486-8058
Tingting ChenShanghai Key Lab of Reproduction and Development, Shanghai, China.ORCID 0009-0000-7682-512X
Xin LuShanghai Key Lab of Reproduction and Development, Shanghai, China.ORCID 0000-0001-8054-6940
Yan DuClinical Research Unit, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.ORCID 0000-0001-5413-7836
Xiaoni YueShanghai Key Lab of Reproduction and Development, Shanghai, China.ORCID 0009-0000-9267-0981

Funding

National Key Research and Development Program of China 2023YFC2705800Natural Science Foundation of Shanghai Municipality 25ZR1401033
6 · The paper itself

Abstract

backgroundNon-gestational choriocarcinoma (NGCC) is a rare type of malignant tumor. Primary lesions are typically detected in the ovary and rarely invade the corpus uteri and cervix. NGCC usually has a poor prognosis due to the difficulty in achieving early and accurate diagnoses because of its rarity. CASE: This case described a female who was initially diagnosed with gestational choriocarcinoma and treated with EMA-CO chemotherapy. However, subsequent short tandem repeat (STR) analysis confirmed the diagnosis as NGCC, prompting surgical intervention. Given her favorable response and after thorough communication, three additional cycles of EMA-CO chemotherapy were recommended. At her last follow-up, her human chorionic gonadotropin level had normalized.

conclusionThis case presents a rare instance of NGCC with simultaneous uterine and cervical involvement, confirmed by STR analysis and successfully managed with the EMA-CO regime. It highlights the necessity of precise diagnosis and personalized treatment for effective management of this disease.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsChoriocarcinoma, Non-gestationalPrecision MedicineUterine Cervical NeoplasmsUterine NeoplasmsAdultCervix UteriCyclophosphamideDactinomycinEtoposideFemaleHumansMethotrexatePregnancyVincristineCyclophosphamideDactinomycinEtoposideMethotrexateVincristineEMA‐COgestational choriocarcinomahCGnon‐gestational choriocarcinomashort tandem repeat

Identifiers

PMID41195577
PMCPMC12590156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.