Evidence map›Paper›PMID 41195564›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Stromal Cell-Mast Cell Communication Orchestrates Anti-Viral Immunity in the Meninges.

Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Stromal Cell-Mast Cell Communication Orchestrates Anti-Viral Immunity in the Meninges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qingqing LiInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.
Weijia ChenInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.
Mengxue SunInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.
Xinbo NiInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.
Qishan RanDepartment of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Xiaoyu HuInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.
Fang CaoDepartment of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Wenwen ZengInstitute for Immunology and School of Basic Medical Sciences, Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing, 100084, China.ORCID https://orcid.org/0000-0001-8544-3318

Funding

Center for Life SciencesInstitute for Immunology, and School of Basic Medical Sciences at Tsinghua UniversityNational Key R&D Program of China 2023YFC2306300National Natural Science Foundation of China 32225019National Natural Science Foundation of China 32394003National Natural Science Foundation of China 82260260National Natural Science Foundation of China 92357304
6 · The paper itself

Abstract

Mast cells are tissue-resident immune sentinels. However, their spatial localization and potential role in the antiviral response within the meninges-the protective barrier surrounding the central nervous system-remain unclear. Here, the distribution pattern along meningeal vasculature is maped and identified a post-weaning maturation process. Single-cell RNA sequencing reveals that mast cells mount a robust immune response against LCMV infection. Ablation of mast cells results in reduced CD8

Indexed as

Cell CommunicationLymphocytic ChoriomeningitisMast CellsMeningesStromal CellsAnimalsCD8-Positive T-LymphocytesInterleukin-33Lymphocytic choriomeningitis virusMiceMice, Inbred C57BLInterleukin-33IL‐33mast cellsmeningesstromal cellsviral infection

Identifiers

PMID41195564
PMCPMC12850450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.