Evidence map›Paper›PMID 41195384›Full record

ReviewFrontiers in physiology2025

Intelligent monitoring and individualized strategies for preventing altitude sickness during altitude training.

Longji Li, Tianfei Fan, Zhijie Luo, Peixin Zhu, Lifeng Zhang

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Longji LiStrength and Conditioning Center, School of Physical Education, Chengdu Sport University, Chengdu, China.
Tianfei FanDepartment of Pharmacy, West China Hospital, Sichuan University, Chengdu, China.
Zhijie LuoStrength and Conditioning Center, School of Physical Education, Chengdu Sport University, Chengdu, China.
Peixin ZhuStrength and Conditioning Center, School of Physical Education, Chengdu Sport University, Chengdu, China.
Lifeng ZhangStrength and Conditioning Center, School of Physical Education, Chengdu Sport University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Altitude training is a special training method that uses a hypoxic environment to improve athletic performance. Its scientificity and safety have always attracted much attention. The hypoxic environment at high altitudes causes physiological responses, such as decreased blood oxygen saturation, increased oxidative stress, and changes in vascular permeability. By establishing a multi-level physiological indicator monitoring system, including basic indicator monitoring, special function assessment, and new technology application, the training effect can be effectively evaluated, and the training safety can be guaranteed. In terms of training optimization, the application of individualized programs based on genetic testing and intelligent monitoring systems has significantly improved the scientificity of training. Among them, the step-by-step adaptation method combined with hypoxic pre-training reduce the incidence of acute mountain sickness by 75%, and the individualized program reduce the difference in training effects by 40%. However, altitude training still faces controversial issues such as the ethics of drug intervention and the effect of simulated training. Future research should focus on the gene-environment interaction mechanism, develop new monitoring technologies, and establish a multidisciplinary collaboration system. This review focuses on the physiological mechanisms, monitoring methods, optimization strategies, limitations and future development directions of altitude training in preventing altitude sickness. This provides an important basis for the scientific practice of altitude training. By continuously optimizing the training system, altitude training will become a safe and effective method to improve athletic performance and prevent altitude sickness.

Indexed as

altitude sicknessaltitude traininghypoxic adaptationintelligent monitoringpersonalized intervention

Identifiers

PMID41195384
PMCPMC12584771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.