Evidence map›Paper›PMID 41195326›Full record

ArticleACS applied nano materials2025

Supramolecular Aggregation-Induced Emission Photosensitizer Encapsulated by Cucurbit[8]uril Nanocavity Boosts Hypoxia-Activated Tumor Therapy.

Wen Liu, Zeyu Zhang, Qing Huang, Rishi Pai, Lucas Liu, Zufeng Ding, Xing Wang, Zhicheng Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied nano materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wen LiuDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID https://orcid.org/0009-0001-9333-2981
Zeyu ZhangDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.
Qing HuangDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.
Rishi PaiDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.
Lucas LiuDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID https://orcid.org/0009-0007-7811-5421
Zufeng DingDepartment of Biology, Georgia State University, Atlanta, Georgia 30303, United States.ORCID https://orcid.org/0000-0001-8643-7059
Xing WangDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID https://orcid.org/0000-0002-6080-4540
Zhicheng JinDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID https://orcid.org/0000-0001-6072-7533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited efficacy of chemotherapy induced by the hypoxic tumor microenvironment remains a major obstacle in clinical oncology. To address this, we designed and synthesized a series of aggregation-induced emission photosensitizers with donor-π-acceptor structures, exemplified by SC-3. Upon assembly with cucurbit[8]-uril (CB[8]), the nanosupramolecular photosensitizer 2SC-3/CB[8] significantly enhanced singlet oxygen (

Indexed as

aggregation induced emission (AIE)hypoxiaphotodynamic therapyself-assemblysupramolecular photosensitizer

Identifiers

PMID41195326
PMCPMC12584102

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.