ArticleFrontiers in endocrinology2025
The ProCVT smart-sheet as a new screening tool for cardiovascular autonomic neuropathy: a feasibility study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Diagnostic accuracy of the COMPASS-31 orthostatic intolerance domain for detecting cardiovascular autonomic neuropathy in resource-limited settings.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Body mass index, sedentary lifestyle, and HbA1c predict cardiac autonomic neuropathy in type 2 diabetes.Cardiovascular diabetology. Endocrinology reports · 2026Article
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5 authors.
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Abstract
Introduction: Cardiovascular autonomic neuropathy (CAN) is a severe complication of diabetes that impairs the regulation of the cardiovascular system. This can cause hemodynamic instability, arrhythmias, and silent ischemia. Despite its clinical significance, routine testing is not widely implemented. Therefore, this study investigated the performance of a novel screening tool, the Methods: Forty individuals with T2D (aged 45-75) with varying degrees of CAN and 20 age-matched controls were included in this cross-sectional study. Autonomic profiling included cardiovascular autonomic reflex tests, short-term CVT, 72-hour blood pressure monitoring, and three nights of home monitoring with the Results: A total of 164 recordings were obtained, with an average of 93% of each recording classified as very high signal quality before artifact removal. Short- and long-term mean CVT were the best-performing parameters, identifying any and manifest CAN with AUCs of 0.64-0.79. Suggested cut-offs were 2.7 linear vagal scale (LVS) units for short-term and 5.0 LVS for long-term recordings. Conclusion: The
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