Evidence map›Paper›PMID 41195156›Full record

ReviewScientifica2025

Bacterial Leakage Testing in Dentistry: A Comprehensive Review on Methods, Models, and Clinical Relevance.

Niher Tabassum Snigdha, Mohmed Isaqali Karobari

Abstract readReview
In one paragraph

Review in Scientifica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Niher Tabassum SnigdhaDepartment of Dental Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, Tamil Nadu, India.
Mohmed Isaqali KarobariDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-0313-9695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The marginal gap increases the rate of bacterial leakage and treatment failure; the measurement of the marginal gap is questionable. The literature revealed that when bacteria get trapped within the smear layer, they can multiply and re-contaminate the root canal system, leading to treatment failure. Methodology: A literature search was carried out in multiple databases, including PubMed, Web of Science, Scopus, and ScienceDirect, with the help of MeSH terms such as Bacterial infection, Bacterial leakage, Dental leakage, Dental material, Root canal preparation, Root canal obturation, and Tooth penetration. Result: The initial result of the search showed 2252 articles that were relevant enough. However, only 26 articles were eligible based on inclusion criteria. Conclusion: The bacterial leakage test can evaluate one of the most essential properties of dental material: sealing ability. The sealing ability of a dental material can prevent bacterial ingestion and reduce the treatment failure rate. This study discussed all the steps of the bacterial leakage test in detail. This study can help the researcher plan and run a bacterial leakage study successfully, and the results can help clinicians choose the best sealing material for the clinical scenario.

Indexed as

bacterial infectionbacterial leakage testdentaldental leakagedental materialroot canal obturationroot canal preparationtooth penetration

Identifiers

PMID41195156
PMCPMC12585858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.