ArticleBiomaterial investigations in dentistry2025
The impact of storage protocols on the mechanical and structural properties of frozen platelet-rich fibrin membranes.
Article in Biomaterial investigations in dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Frozen advanced platelet-rich fibrin as an adjunct to the modified tunnel technique for root coverage: A pilot randomised clinical trial.Journal of Indian Society of PeriodontologyArticle
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7 authors.
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Abstract
Background & objectives: Platelet-rich fibrin (PRF) has shown promise in periodontal surgery and is found to promote bone regeneration. However, its limitations include low elasticity, short lifespan, and poor storage stability. This study aimed to overcome these limitations by developing frozen PRF and comparing the mechanical and structural properties of advanced-PRF (A-PRF) and two frozen PRF storage protocols. Methodology: This Results: Comparing three PRF membranes, Fz-PRF7 showed significantly higher tensile strength than A-PRF and Fz-PRF1, and higher modulus of elasticity than A-PRF. However, SEM analysis revealed no significant differences in BEAI and fibrin density scores across groups. Conclusion: Fz-PRF7 showed improved mechanical properties, specifically tensile strength and elasticity, compared to A-PRF, overcoming some limitations of conventional PRF.
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