ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2025
Tomotherapy megavoltage computed tomography for lung tumor positioning and contouring.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The study aim was to evaluate the usefulness of tomotherapy megavoltage computed tomography (MVCT) as "slow" CT for both positioning and contouring lung tumors. Materials and methods: Cranio-caudal motion of a pulmonary lesion was simulated by using a QUASAR phantom for different breathing periods (2-10 s) and cycles (sine and cosine-fourth-power). Coronal and sagittal MVCT reconstructions were analyzed, and Dice similarity coefficients were obtained to compare the expected motion-encompassing volumes with the segmented volumes. Results: Despite motion artifacts in axial slices, the coronal and sagittal midplanes allowed delineation of the internal treatment volume, except when the breathing period was equal to the acquisition time (5 s). In that case, an aliasing artifact prevented applying proper delimitation. The highest similarity coefficient (> 0.9) was obtained for the lowest CT spacing (2 mm) and the shortest breathing period. Conclusions: For periodic breath patterns, Tomotherapy MVCT can be used for positioning and cranio-caudal length contour delineation of lung tumors in motion.
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