Evidence map›Paper›PMID 41194982›Full record

ArticleFrontiers in bioengineering and biotechnology2025

The impact of lateral ankle ligament injuries on ankle stability and talar cartilage stress: a finite element analysis of combined injury mechanisms.

Shuai Ji, Liang Sun, Qian Wang, Hongfei Qi, Bo Wu, Bing Du, Chengcheng Zhang, Kun Zhang, Zhong Li, Ming Li and 1 more

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mechanical Contribution of the Anterior Talofibular Ligament to Ankle Stability: 3D Anatomical Finite Element Analysis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuai Ji *Department of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Liang Sun *Department of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Qian WangDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Hongfei QiDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Bo WuDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Bing DuDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Chengcheng ZhangDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Kun ZhangDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhong LiDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Ming LiDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yao LuDepartment of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the differential biomechanical effects of injuries to the superior and inferior fascicles of the anterior talofibular ligament (ATFL) and the calcaneofibular ligament (CFL) on ankle stability and talar cartilage stress, providing a basis for the Fascicle-specific diagnosis and treatment of chronic ankle instability. Methods: A finite element model incorporating bones, articular cartilage, and nine sets of ligament spring elements was created based on CT data from the ankle of a 26-year-old male volunteer. Six conditions were simulated: 1. intact model; 2. superior ATFL Fascicle injury; 3. inferior ATFL Fascicle injury; 4. complete ATFL injury (superior + inferior Fascicles); 5. CFL injury; and 6. combined ATFL + CFL injury. Anterior drawer test (100 N anterior traction), varus stress test (1.7 N·m torque), and single-leg standing test (600 N axial load) were performed to measure talar displacement and cartilage stress distribution. Results: 1. In the anterior drawer test, talar displacement was greater in superior ATFL Fascicle injuries than in inferior ATFL Fascicle and CFL injuries. 2. In the inversion test, talar displacement was greater in CFL injuries than in superior, inferior, or complete ATFL injuries. 3. In the single-leg standing test, all five injury models altered the contact stress distribution on the talar cartilage compared to the intact model, shifting the peak stress from the anterolateral dome to the anteromedial dome and increasing pressure on the anteromedial talar dome. The peak stress magnitudes were ranked as follows: ATFL + CFL injury > complete ATFL injury > superior ATFL Fascicle injury > inferior ATFL Fascicle injury > CFL injury. 4. The combined ATFL + CFL injury model showed significantly greater displacement and peak stress than the other four injury models. Conclusion: The superior Fascicle of the ATFL is the primary restraint for anterior stability; the CFL dominates rotational stability; combined injuries trigger a biomechanical cascade failure; lateral ankle ligament injuries lead to increased contact stress on the anteromedial talar cartilage, contributing to the development of arthritis.

Indexed as

ankle lateral collateral ligamentanterior talofibular ligamentbiomechanicscalcaneofibular ligamentfinite element

Identifiers

PMID41194982
PMCPMC12583215

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.