ArticleFrontiers in bioengineering and biotechnology2025
Nano-thin amorphous tantalum-coated prosthesis for acetabular bone defect reconstruction:
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The optimal reconstruction method for complex bone defects remains controversial. This study aims to introduce the innovative concepts of nano-thin tantalum coating titanium-based prostheses in treating complex acetabular bone defects. Method: Ten minipigs were used for Results: All three types of scaffolds had satisfactory bone in-growth, while TC4 scaffolds still seemed inferior to pure Ta scaffolds and Ta-coated scaffolds in terms of early-stage bone in-growth rate. Totally 3 patients were enrolled in clinical series, with an average follow-up period of 21.7 months. All patients successfully underwent surgery. At the latest follow-up, all patients exhibited significant improvements in pain symptoms (as assessed by VAS) and HHS scores. No severe complications such as infection, prosthesis loosening, or vascular and nerve injuries were observed in any patient. Conclusion:
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