ArticleFrontiers in bioengineering and biotechnology2025
The effects of needle and warm needle on hemodynamic responses at different acupoints in patients with knee osteoarthritis.
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Bridging physics and biology in acupuncture: flexible multimodal bioelectronics for decoding the deqi microenvironment.Frontiers in bioengineering and biotechnology · 2026Review
- Pain Modulation, Inflammation-Regulatory Mechanisms, and Translational Boundaries of Evidence for Acupuncture-Related Therapies in Knee Osteoarthritis: A Structured Narrative Review.Journal of pain research · 2026Review
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Authors and funding
8 authors.
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Abstract
Background: Acupuncture, as a non-pharmacological alternative therapy, has been widely used in China for the clinical treatment of knee osteoarthritis (KOA). Different acupuncture methods and acupoint selections are two critical factors influencing clinical efficacy. Although multiple studies have confirmed the efficacy of acupuncture in treating KOA, its underlying physiological mechanisms remain unclear. Objective: This study aimed to explore hemodynamic responses in KOA patients before and after interventions with different acupuncture methods and acupoint combinations, monitoring hemodynamic changes during acupuncture using near-infrared spectroscopy (NIRS). Methods: A total of 24 KOA patients received needle and warm needle interventions at SP10 ( Results: Compared with needle, warm needle significantly increased HbO Conclusion: Our study provides the first evidence that different combinations of acupuncture methods and acupoint selections can significantly affect hemodynamic responses. Warm needle significantly improved local blood flow and oxygen delivery capacity in KOA patients, maintaining these improvements longer than needle intervention. Furthermore, warm needle at SP10 demonstrated superior efficacy in improving oxygen metabolism compared to ST34.
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