ArticleMedical journal of the Islamic Republic of Iran2025
Comparison between Tracheostomy and No Tracheostomy on the Incidence of Ventilator-Associated Pneumonia (VAP) Using the Modified Clinical Pulmonary Infection Score (MCPIS): A Prospective Cohort Study.
Article in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Tracheostomy and Ventilator-Associated Pneumonia in Mechanically Ventilated ICU Patients: A Retrospective Matched Cohort Study.Journal of clinical medicine · 2026Article
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5 authors.
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Abstract
Background: The principal mechanism underlying the development of ventilator-associated pneumonia (VAP) involves the aspiration of microorganisms from colonized oropharyngeal secretions past the endotracheal tube (ETT), followed by bacterial proliferation along the ETT surface. The Modified Clinical Pulmonary Infection Score (MCPIS) is commonly utilised to assist in the diagnosis and clinical evaluation of pneumonia. This instrument assesses various factors, including body temperature, leukocyte count, the volume and characteristics of tracheal secretions, oxygenation status, and results from chest imaging. Airway management through ETT intubation or tracheostomy plays a crucial role in ensuring airway patency, minimizing anatomical dead space, facilitating effective suctioning, and optimizing oxygen delivery. Methods: This prospective cohort study included individuals diagnosed with non-traumatic brain damage, selected using successive sampling according to established inclusion and exclusion criteria. The sample size was established at a 90% confidence level and a precision of 20%, with statistical significance defined at p < 0.05. The research was carried out at Wahidin Sudirohusodo Hospital in Makassar, from March 2024 to April 2025, and involved evaluating the MCPIS both before and after tracheostomy, as well as in patients who did not undergo the procedure. Data analysis was conducted using SPSS version 25, applying the Wilcoxon Signed-Rank test to assess statistical differences. Results: A total of 50 samples were included (25 with tracheostomy and 25 without). When the average MCPIS scores were analyzed, the tracheostomy group's score dropped from 4.92 to 3.20 ( Conclusion: Tracheostomy was associated with improved MCPIS outcomes compared to non-tracheostomy, particularly in the components of temperature, tracheal secretion, and oxygenation.
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