Evidence map›Paper›PMID 41194850›Full record

ReviewCureus2025

Radiotherapy for Keloids: A Comprehensive Narrative Review.

Hsin-Hua Nien, Pei-Chieh Yu, Yu-Hsiu Yen, Yu-Lun Tsai, Li-Ying Wang, Chen-Hsi Hsieh

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hsin-Hua NienDepartment of Radiation Oncology, Cathay General Hospital, Taipei, TWN.
Pei-Chieh YuDepartment of Radiation Oncology, Cathay General Hospital, Taipei, TWN.
Yu-Hsiu YenSchool of Medicine, Fu Jen Catholic University, Taipei, TWN.
Yu-Lun TsaiDepartment of Radiation Oncology, Cathay General Hospital, Taipei, TWN.
Li-Ying WangSchool and Graduate Institute of Physical Therapy, National Taiwan University College of Medicine, Taipei, TWN.
Chen-Hsi HsiehDivision of Radiation Oncology, Department of Radiology, Far Eastern Memorial Hospital, Taipei, TWN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keloids cause uncomfortable symptoms that disrupt daily life. The outcomes of monotherapy are often unsatisfactory. However, surgical excision followed by adjuvant radiotherapy has been shown to reduce recurrence rates. Radiotherapy for keloid treatment can be administered using various radiation modalities and sources. Each radiation modality and source has unique treatment properties and requires careful setup considerations. Treatment parameters and variability in clinical outcomes and adverse effects have been reported across studies. This literature review aimed to provide a narrative overview of the differences and defining characteristics of each radiation modality used in keloid management and to summarize the clinical evidence supporting their treatment efficacy. Radiation treatment regimens, recurrence rates, and adverse effects were summarized according to modality. The factors affecting treatment efficacy were analyzed. A comprehensive understanding of each radiation modality's properties enables the development of institution-specific treatment strategies, tailored to available resources and supported by multidisciplinary collaboration. Cautious planning and delivery of radiotherapy, combined with surgery, can result in favorable clinical outcomes for patients with keloids.

Indexed as

brachytherapyelectronexternal beam radiotherapykeloidphotonradiotherapy

Identifiers

PMID41194850
PMCPMC12584881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.