L-arginine Results in an Artificial Increase in Creatinine.

Michelle Hwang, Jennifer Han, Sean Lei, Igor Kagan

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle HwangMedicine, Ronald Reagan University of California Los Angeles Medical Center, Los Angeles, USA.

Jennifer HanEndocrinology, Diabetes and Metabolism, University of California Los Angeles David Geffen School of Medicine, Los Angeles, USA.

Sean LeiNephrology, Ronald Reagan University of California Los Angeles Medical Center, Los Angeles, USA.

Igor KaganNephrology, Ronald Reagan University of California Los Angeles Medical Center, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-arginine is a commonly available over-the-counter supplement. We report a 65-year-old man with a history of benign prostatic hyperplasia, hypertension, and obstructive sleep apnea who had an elevated serum creatinine level and normal cystatin C in the setting of L-arginine supplementation. After discontinuation of L-arginine, repeat testing showed normalization of serum creatinine, while cystatin C remained unchanged, thus demonstrating that L-arginine use can result in an artificial increase in serum creatinine.

Indexed as

artificial increase in creatininecystatin cincrease in creatininel-argininesupplement

Identifiers

PMID41194845

DOI10.7759/cureus.93866

PMCPMC12584855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.