Evidence map›Paper›PMID 41194667›Full record

Observational studyPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2025

Does cytomegalovirus infection increase the risk of tuberculosis in UK children?

Sarah May Johnson, Elizabeth Whittaker, James Seddon, Beate Kampmann, Helen Payne

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The indirect effects of cytomegalovirus infection-mechanisms and consequences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah May JohnsonDepartment of Paediatric Infectious Diseases, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0001-8848-9135
Elizabeth WhittakerDepartment of Paediatric Infectious Diseases and Immunology, Imperial College London, London SW7 2AZ, UK.
James SeddonDesmond Tutu TB Centre, Stellenbosch University, Stellenbosch 7505, South Africa.
Beate KampmannThe Vaccine Centre, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Helen PayneDepartment of Paediatric Infectious Diseases, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-7083-9384

Funding

NIHRWellcome Trust
6 · The paper itself

Abstract

There is a hypothesized association between pre-existing cytomegalovirus (CMV) infection and risk of acquiring tuberculosis (TB). We aimed to explore if CMV seroprevalence and CMV IgG levels in children were associated with TB disease or

Indexed as

Cytomegalovirus InfectionsTuberculosisChildChild, PreschoolCohort StudiesCross-Sectional StudiesCytomegalovirusFemaleHumansImmunoglobulin GMaleMycobacterium tuberculosisRisk FactorsSeroepidemiologic StudiesUnited KingdomImmunoglobulin GchildrencytomegalovirusTB exposuretuberculosis

Identifiers

PMID41194667
PMCPMC12590162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.