Evidence map›Paper›PMID 41194662›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2025

The immune response to human cytomegalovirus: impact of age, co-morbidities and the significance of anti-viral activity assessment.

Sarah Elizabeth Jackson, Mahlaqua Noor, Eleanor Lim, Mark Wills

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The indirect effects of cytomegalovirus infection-mechanisms and consequences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah Elizabeth JacksonMedicine and CITIID, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.ORCID 0000-0002-4230-9220
Mahlaqua NoorMedicine and CITIID, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.
Eleanor LimMedicine and CITIID, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.
Mark WillsMedicine and CITIID, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.ORCID 0000-0001-8548-5729

Funding

Addenbrooke's Charitable Trust, Cambridge University HospitalsGates Cambridge TrustMedical Research CouncilWellcome Trust
6 · The paper itself

Abstract

Understanding how all the components of the immune system respond to human cytomegalovirus (HCMV) primary infection and subsequent reactivation events is necessary to be able to successfully treat patients suffering from HCMV-mediated disease. In the first part of this review, we overview the humoral response to HCMV, followed by sections on the response of NK cells, CD8

Indexed as

AgingAntiviral AgentsCytomegalovirusCytomegalovirus InfectionsAge FactorsComorbidityHumansImmunocompromised HostAntiviral Agentsantibodyanti-viralimmune-evasionimmunosenescenceNK-cellT-cells

Identifiers

PMID41194662
PMCPMC12590175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.