ReviewThe FEBS journal2026
Multifaceted multivalency with a hub protein.
Review in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Recent investigations into the interaction between LC8 and GKAP significantly contribute to our understanding of LC8 multivalency. This comprehensive approach addresses four features we find vital for elucidating the mechanisms governing polybivalent complexation behavior: registration control, binding motifs, linker lengths, and flexibility. By deepening our understanding of these characteristics, we move closer to predicting critical aspects of LC8-partner interactions, including whether partners assemble homogeneously or heterogeneously, the degree of flexibility between adjacent binding sites, the strength of binding, and, importantly, the functional consequences of these interactions solely based on the sequence of LC8 binding partners.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.