Evidence map›Paper›PMID 41194477›Full record

ArticleBrain and behavior2025

Epidemiology of Parkinson's Disease in Germany Between 2016 and 2021 Based on Statutory Health Insurance Claims Data.

Dirk Woitalla, Gisa Ellrichmann, Stefan Jun Groiss, Stefan Walzer, Lutz-Michael Vollmer, Signe Thiesen-Nash, Sebastian Krenberger, Julia Borchert, Glynn Harrison-Jones

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dirk WoitallaDepartment of Neurology, St. Josef-Krankenhaus Kupferdreh, Essen, Germany.
Gisa EllrichmannFaculty of Health/School of Medicine, Chair of Neurology II, Witten/Herdecke University, Witten, Germany.
Stefan Jun GroissNeuro-Centrum Düsseldorf, Düsseldorf, Germany.
Stefan WalzerMArS Market Access & Pricing Strategy GmbH, Weil am Rhein, Germany.
Lutz-Michael VollmerMArS Market Access & Pricing Strategy GmbH, Weil am Rhein, Germany.
Signe Thiesen-NashBIAL Deutschland GmbH, Mörfelden-Walldorf, Germany.
Sebastian KrenbergerMArS Market Access & Pricing Strategy GmbH, Weil am Rhein, Germany.ORCID https://orcid.org/0000-0003-4608-5380
Julia BorchertWIG2 GmbH, Leipzig, Germany.
Glynn Harrison-JonesBIAL Pharma UK Ltd., Windsor, UK.ORCID https://orcid.org/0009-0006-4201-5886

Funding

BIAL - Portela & Ca, S.A.
6 · The paper itself

Abstract

introductionParkinson's disease (PD) is a fast-growing neurodegenerative disease causing a high burden on national health systems. There is a lack of contemporary, reliable epidemiological data for PD in Germany. The aim of this study was to estimate the incidence and prevalence of PD in Germany for the years 2016-2021.

methodsThis is a secondary data analysis of anonymized health claims data from a subset of German statutory health insurances (SHIs) for the years 2016-2021. Data were then extrapolated to represent the full SHI population.

resultsFrom 2016 to 2021, PD prevalence in the study population increased from 494 to 511 patients per 100,000 (p = 0.0067). Incident patients showed no change overall but notably decreased from 2019 to 2020. In contrast, PD prevalence in the extrapolated cohort declined significantly during the same period, dropping from 575 to 501 patients per 100,000 (p < 0.0001). Similarly, PD incidence decreased from 69 to 60 patients per 100,000 (p = 0.0001).

conclusionsPD prevalence increased in the study population but declined in the extrapolated cohort, while incidence remained stable overall in the study population, yet decreased in the extrapolated cohort. This study provides key insights into the epidemiology of PD in Germany, highlighting the influence of methodology and the need for ongoing monitoring to inform healthcare planning.

Indexed as

Parkinson DiseaseAdultAgedAged, 80 and overFemaleGermanyHumansIncidenceInsurance, HealthMaleMiddle AgedPrevalenceepidemiology of Parkinson's disease by genderincidence of Parkinson's diseaseParkinson's disease with dementiaprevalence of Parkinson's disease

Identifiers

PMID41194477
PMCPMC12589807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.