Evidence map›Paper›PMID 41194314›Full record

ArticleClinical oral implants research2026

The Effect of Defect Morphology and Membrane Fixation on 3D Graft Material Displacement During Primary Wound Closure in Horizontal Bone Augmentation-An Ex Vivo Study.

Clemens Raabe, Emilio A Cafferata, Wenjie Zhou, Katharina M Müller, Neelam Lingwal, Ausra Ramanauskaite, Frank Schwarz, Emilio Couso-Queiruga

Abstract read
In one paragraph

Article in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. A Review of Synthetic Bone Grafts in Lumbar Interbody Fusion.Bioengineering (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clemens RaabeDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0003-2659-3505
Emilio A CafferataDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0001-9243-1382
Wenjie ZhouDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0001-8158-253X
Katharina M MüllerDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0001-8121-5246
Neelam LingwalDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.
Ausra RamanauskaiteDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0002-1649-1882
Frank SchwarzDepartment of Oral Surgery and Implantology, Goethe University, Carolinum, Frankfurt am Main, Germany.ORCID 0000-0001-5515-227X
Emilio Couso-QueirugaDepartment of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0002-9989-4483

Funding

Clinical Research Foundation for the Promotion of Oral HealthStiftung Professor Dr. Max Cloëtta
6 · The paper itself

Abstract

objectivesThis preclinical study evaluated the influence of two defect morphologies on graft material displacement (GMD) during primary wound closure in horizontal bone augmentation (HBA). Secondary aims included assessing the effect of membrane stabilization and the role of local soft tissue characteristics on GMD. MATERIALS AND

methodsStandardized HBA procedures following guided bone regeneration principles were performed on fresh pig hemimandibles. Each mandible received two sequential HBAs, randomized for defect morphology-partially contained (PCD) vs. contained (CD)-and membrane stabilization with (+Pins) or without (-Pins) four fixation pins. GMD was assessed using cone-beam computed tomography and intraoral scanning by comparing graft dimensions before and after wound closure, at nine levels from the implant platform and across nine delimited sections, respectively.

resultsSixty HBA procedures were analyzed. A notable GMD was observed for both PCD and CD, with no significant differences between them. In contrast, membrane stabilization significantly reduced three-dimensional GMD across all sections, with the most pronounced effect in the central-crestal section (p < 0.001). At the implant platform level, GMD was -15.8% ± 25.6% with pins vs. -38.1% ± 27.4% without pins (p < 0.001). Across all groups, GMD occurred in an apico-lateral direction, with the greatest volume loss in the central-crestal, mesial, and distal crestal sections. Soft tissue phenotype did not affect GMD (p ≥ 0.240).

conclusionDefect morphology did not significantly influence the notable apico-lateral GMD. However, membrane stabilization using pins effectively reduced graft displacement, minimizing movement during primary wound closure.

Indexed as

Alveolar Ridge AugmentationBone TransplantationGuided Tissue Regeneration, PeriodontalMandibleWound Closure TechniquesAnimalsCone-Beam Computed TomographySwineWound Healingalveolar ridge augmentationbone substitutescone‐beam computed tomographydental implantsgraftsguided bone regenerationsurgical flaps

Identifiers

PMID41194314
PMCPMC12975682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.