Metabolic syndrome and health-related quality of life: unraveling the role of gender (A SUMS employees cohort-based study).

Fatemeh Rezaei Chegini, Mozhgan Seif, Mohebat Vali, Seyed Jalil Masoumi, Haleh Ghaem

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Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Fatemeh Rezaei CheginiStudent Research Committee, Shiraz University of Medical Science, Shiraz, Iran.

Mozhgan SeifDepartment of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

Mohebat ValiNon-Communicable Diseases Research Center, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

Seyed Jalil MasoumiNutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Science, Shiraz, Iran. sjm@sums.ac.ir.

Haleh GhaemResearch Center for Health Sciences, Institute of Health, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. ghaemh@sums.ac.ir.

Funding

Vice-Chancellor for Research, Shiraz University of Medical Sciences 29569

6 · The paper itself

Abstract

objectiveMetabolic syndrome (MetS), beyond its well-established link to the rising tide of chronic conditions, casts a significant shadow on individual's daily well-being, diminishing their Health-related quality of life (HRQOL). This study examines the association between MetS and HRQOL with a focus on gender differences among a cohort of healthcare workers.

resultsIn this study, the prevalence of MetS was 9.3%, with a higher prevalence in men (10.3%) than in women (8.5%). Women with MetS reported significantly lower overall HRQOL scores compared to women without MetS (β = -1.89, p< 0.001), while no such association was found in men (β = 0.05, p = 0.922). Additionally, a significant gender-dependent interaction was observed, with a stronger association between MetS and lower physical HRQOL scores in women than in men (β = -3.17 vs. β = -2.17). Findings highlight a gender-specific pattern in the association between MetS and reduced HRQOL, emphasizing the need for targeted interventions.

Indexed as

Health PersonnelMetabolic SyndromeQuality of LifeAdultCohort StudiesFemaleHumansMaleMiddle AgedPrevalenceSex FactorsGender differencesHealthcare workersHealth-related quality of lifeMetabolic syndrome

Identifiers

PMID41194286

DOI10.1186/s13104-025-07532-5

PMCPMC12587520

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LicenceCC BY-NC-ND

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