Evidence map›Paper›PMID 41194278›Full record

ArticleDiabetology & metabolic syndrome2025

Association between physical activity propensity and cardiovascular autonomic neuropathy in type 1 diabetes: evidence from a single-centre study.

Simona Zaccaria, Laura Giurato, Isabella Nardone, Sium Wolde Sellasie, Innocenza Tripicchio, Marco Meloni, Pasquale Di Perna, Luigi Uccioli

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Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Simona ZaccariaDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy. simona.zaccaria@alumni.uniroma2.eu.
Laura GiuratoDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.
Isabella NardoneDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.
Sium Wolde SellasieDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.
Innocenza TripicchioDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.
Marco MeloniDepartment of Sistems Medicine, University of Rome Tor Vergata, Rome, 00133, Italy.
Pasquale Di PernaDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.
Luigi UccioliDivision of Endocrinology and Diabetes, Department of Surgical Sciences, CTO Andrea Alesini Hospital, University of Rome Tor Vergata, Rome, 00133, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to investigate whether recent physical activity (PA), assessed in a real-world outpatient setting, is associated with a lower prevalence of cardiovascular autonomic neuropathy (CAN) in individuals with type 1 diabetes.

methodsSixty-six patients with type 1 diabetes were tested for CAN using cardiovascular reflex tests. PA level was assessed using the International Physical Activity Questionnaire (IPAQ) and patients were classified into low, moderate, or high PA groups.

resultsPA was low in 13 (19.7%), moderate in 19 (28.8%) and high in 34 (51.5%) patients. Fisher's exact test conducted to examine the relationship between PA groups and diabetic CAN categories revealed a statistically significant difference (p < 0.001) being absent in 67.7% and early in 29.4% of the patients belonging to the high PA group. In addition, engagement in at least 600 MET minutes per week was independently associated with a lower probability of having CAN (OR = 0.131, 95% CI: 0.017-0.986, p = 0.048).

conclusionsHigher levels of self-reported physical activity are associated with a reduced likelihood of CAN in patients with type 1 diabetes. These findings support the importance of promoting regular PA as part of routine diabetes care.

Indexed as

Cardiovascular autonomic neuropathyIPAQPhysical activityType 1 diabetes mellitus

Identifiers

PMID41194278
PMCPMC12587556

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