Evidence map›Paper›PMID 41194276›Full record

ArticlePerioperative medicine (London, England)2025

Application of high-flow nasal oxygen during anesthesia induction for frame-based stereoelectroencephalography: a randomized controlled non-inferiority trial.

Xiaofen Sun, Mingming Han, Zefeng Fan, Xiang Huang, Fang Kang, Juan Li

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Article in Perioperative medicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiaofen SunDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Mingming HanDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Zefeng FanDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xiang HuangDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Fang KangDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Juan LiDepartment of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. huamuzi1999@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-flow nasal oxygen (HFNO) is increasingly used for preoxygenation and apneic oxygenation; however, its efficacy during anesthesia induction for frame-based stereoelectroencephalography (SEEG) remains uncertain. This study evaluated whether HFNO is non-inferior to facemask ventilation in maintaining oxygenation during anesthesia induction for frame-based SEEG.

methodsIn this randomized, controlled, non-inferiority trial, adult patients with refractory epilepsy undergoing frame-based SEEG were randomized to either the HFNO or facemask group. The primary endpoint was the lowest peripheral oxygen saturation (SpO

resultsAmong 46 patients, the median (interquartile range [IQR]) lowest SpO

conclusionHFNO is non-inferior to facemask ventilation in maintaining oxygenation during anesthesia induction for frame-based SEEG. Moreover, HFNO reduces the need for airway adjuncts, shortens airway securement time, and enhances both patient and anesthesiologist satisfaction.

trial registrationThis study was registered in the Chinese Clinical Trial Registry (ChiCTR2100044239; first registration date: March 12, 2021; https://www.chictr.org.cn/showproj.html?proj=119780 ).

Indexed as

Apneic oxygenationFacemask ventilationGeneral anesthesiaHigh-flow nasal oxygenPreoxygenationStereoelectroencephalography

Identifiers

PMID41194276
PMCPMC12590915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.