ArticleBMC chemistry2025
Dual-functional nitrogen-doped carbon dot/copper oxide nanocomposites for electrochemical sensing of ascorbic acid and antimicrobial applications.
Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Development of resveratrol-loaded hollow mesoporous silica enhances mechanical performance and biocompatibility of dental resin cement.Discover nano · 2026Article
- Bio-derived NiO nanoparticles fromRSC advances · 2026Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance poses a growing threat to effective infection treatment, while imbalances in ascorbic acid (AA) levels are linked to various health issues. Nanotechnology offers innovative solutions, with carbon dot-based nanocomposites emerging as promising materials for both antimicrobial applications and sensitive detection of biomolecules. This study aimed to synthesize nitrogen-doped carbon dots (NCDs), copper oxide nanoparticles (CuO NPs), and their nanocomposites (CuO-NCDs), and to evaluate their electrochemical sensing of AA and antimicrobial activity.
methodsNCDs were prepared via a hydrothermal treatment of citric acid and urea, and CuO NPs by precipitation of copper nitrate. Characterization by Ultraviolet-Visible (UV-Vis) spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, X-ray Diffraction (XRD), and Scanning Electron Microscopy (SEM) confirmed their optical properties, functional groups, crystallinity, and morphology.
resultsThe CuO-NCD nanocomposite exhibited enhanced optical absorption with a reduced energy band gap (2.6 eV) compared to individual components. Electrochemical tests revealed a detection limit of 2.56 µM for AA and increased electrode surface area, indicating improved sensitivity and selectivity. Antimicrobial assays showed significant activity against Staphylococcus aureus, with a 24 mm inhibition zone at 200 mg/mL after 24 h.
conclusionsThese results demonstrate that CuO-NCD nanocomposites hold potential as dual-function materials for effective AA detection and combating microbial infections.
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