Evidence map›Paper›PMID 41194218›Full record

ArticleJournal of neuroinflammation2025

Desloratadine as the selective 5HT

Dayun Lu, Yuan Ruan, Fan Zhou, Yan Ma, Jieru Chang, Yuxi Wei, Rui Xu, Jiaying Wang, Xu Shen

Abstract read
In one paragraph

Article in Journal of neuroinflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dayun Lu *Jiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yuan Ruan *Department of Endocrinology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China.
Fan ZhouJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yan MaJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jieru ChangJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yuxi WeiJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Rui XuJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jiaying WangJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. wangjy@njucm.edu.cn.
Xu ShenJiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. xshen@njucm.edu.cn.

Funding

Innovation Projects of State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture NZYSKL240110Major Program of the Natural Science Foundation of the Jiangsu Higher Education Institutions of China 23KJA350002National Natural Science Foundation of China 82273930National Natural Science Foundation of China 82473982
6 · The paper itself

Abstract

Diabetic peripheral neuropathy (DPN) is a common diabetic complication with a obscure and complicated pathogenesis. Here, we determined that 5-hydroxytryptamine receptor 2 A (5HT

Indexed as

Diabetic NeuropathiesExtracellular TrapsLoratadineNeutrophilsSerotonin 5-HT2 Receptor AntagonistsAnimalsDiabetes Mellitus, ExperimentalDisease Models, AnimalFemaleGanglia, SpinalHumansMaleMiceMice, Inbred C57BLMiddle AgedReceptor, Serotonin, 5-HT2AdesloratadineLoratadineReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor Antagonists5-hydroxytryptamine receptor 2ADesloratadineDiabetic peripheral neuropathyNeuroinflammation.Neutrophil extracellular trapsVascular dysfunction

Identifiers

PMID41194218
PMCPMC12587694

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.