ArticleJournal of medical case reports2025
In vitro fertilization-assisted pregnancy combined with high-intensity focused ultrasound treatment in patients with endometriosis and adenomyosis with successful pregnancy: a case report.
Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHigh-intensity focused ultrasound ablation has emerged as a noninvasive therapeutic option for adenomyosis of the uterus. We studied a female with infertility patient to explore the application of in vitro fertilization combined with high-intensity focused ultrasound treatment in patients with endometriosis complicated by adenomyosis. CASE PRESENTATION: A retrospective analysis of a 30-year-old Han Chinese woman with infertility complicated by both endometriosis and adenomyosis was performed, including pregnancy achieved through in vitro fertilization, downregulation using a gonadotropin-releasing hormone agonist, high-intensity focused ultrasound treatment and final pregnancy outcomes. The patient successfully conceived following the combined application of high-intensity focused ultrasound treatment and downregulation using a gonadotropin-releasing hormone agonist, with an intrauterine pregnancy confirmed in June 2025 and appropriate fetal development.
conclusionThe combined application of downregulation using a gonadotropin-releasing hormone agonist and high-intensity focused ultrasound treatment represents a promising therapeutic strategy for patients with infertility with concurrent endometriosis and adenomyosis. Nevertheless, prospective multi-centre studies remain essential to validate the long-term efficacy and safety profiles.
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