ArticleBMC ophthalmology2025
Surgical outcomes of Ahmed valve implantation with mitomycin C in glaucoma with and without high myopia.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study aimed to assess the surgical outcomes of Ahmed glaucoma valve (AGV) implantation in high myopic eyes (axial length [AL] of ≥ 26.0 mm) and to determine whether high myopia independently poses a risk of surgical failure.
methodsWe retrospectively reviewed 68 eyes from 59 patients with refractory glaucoma who underwent AGV implantation. Eyes were categorised into high myopia (23 eyes, 33.8%) and control (45 eyes, 66.2%) groups. The primary outcome was the surgical success rate, defined as postoperative intraocular pressure (IOP) of 6-21 mmHg or a ≥ 20% reduction from baseline. Surgical success was further classified into criterion A (postoperative IOP ≤ 21 mmHg) and criterion B (postoperative IOP ≤ 15 mmHg). Surgical success rates were estimated using Kaplan-Meier analysis, and risk factors for surgical failure were identified via Cox proportional hazards modelling.
resultsAt 1 and 2 years, surgical success was significantly higher in the control group according to criterion A (p = 0.013 and 0.043, respectively). Based on criterion B, the control group also showed better surgical success, although the difference did not reach statistical significance. (p = 0.051). Postoperative IOP was lower in the control eyes throughout all postoperative periods, and the difference reached statistical significance at 6 months (p = 0.017). An AL ≥ 26 mm was a significant risk factor for surgical failure under both criterion A (hazard ratio [HR] = 8.30, p = 0.026) and criterion B (HR = 6.26, p = 0.009).
conclusionsAGV implantation in glaucoma eyes with high myopia showed lower surgical success compared to those without high myopia. Longer AL is a significant risk factor for surgical failure, underscoring the importance of careful monitoring after AGV implantation in such cases.
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