Evidence map›Paper›PMID 41193883›Full record

ArticlePharmaceutical medicine2026

The Evolution of Medical Affairs Central Teams: Shaping Strategic Action and Driving Healthcare Transformation Through Scientific Interaction.

Manuel Leal Beckouche, Gustavo Resler Plat, Jorge A Marinich, Carmen Moreno, Marta Moreno, Joana Gostkorzewicz, Inmaculada Iglesias, Ana Pérez Domínguez

Abstract read
In one paragraph

Article in Pharmaceutical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manuel Leal BeckoucheMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Gustavo Resler PlatMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Jorge A MarinichMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Carmen MorenoMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Marta MorenoMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Joana GostkorzewiczMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Inmaculada IglesiasMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Ana Pérez DomínguezMedical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain. Ana.Perez.Dominguez@astrazeneca.com.ORCID 0009-0005-8636-5733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolving role of Medical Affairs (MA) has positioned this department as a key element in the development and lifecycle management of pharmaceutical products. In response to internal and external assessments, AstraZeneca (AZ) Spain implemented a transformation of its MA central teams through a newly designed Working Model. This model ensures full engagement across the product lifecycle, spanning early access, pre-launch, launch, and post-launch, balancing global strategy with local execution, enhancing cross-functional collaboration, and timely evidence generation. Central to this transformation is the deployment of four coordinated teams: the Early Asset Strategy Team, the Launch Readiness Team, the Core Value Team, and the Brand Team. These teams follow a structured work methodology and coordination model underpinned by dedicated information management processes that streamline communication and knowledge transfer. Training and capability-building programmes were also introduced to strengthen critical functional and leadership competencies. These changes aim to improve product positioning, accelerate market access, and drive value-based healthcare outcomes. The initiative aligns with broader industry trends emphasising early stakeholder engagement, data integration, and patient-centric strategies. By fostering agility, strategic foresight, and internal consistency, the transformation of MA central teams at AZ Spain provides a replicable model for enhancing MA's contribution to product development and healthcare ecosystem innovation. This article builds on our previous publications about the national ecosystem assessment of stakeholder needs, the definition of our MA transformation framework (articulating the strategic roadmap), and the description of the evolution of in-field MA teams in AZ Spain. Here we detail the transformation of the MA central teams and their working model. Future MA evolution will integrate emerging technologies like artificial intelligence (AI) and digital tools, improving stakeholder engagement, evidence generation, and decision making. The transformative potential of AI in anticipating trends and optimising trials will enhance the role of MA in driving innovation and improving patient outcomes.

Indexed as

Delivery of Health CareDrug IndustryCooperative BehaviorHumansLeadershipSpain

Identifiers

PMID41193883
PMCPMC12783193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.