Evidence map›Paper›PMID 41193840›Full record

ArticleProtoplasma2026

Phytochemical riches and bioactive potential of Onopordum acanthium L. (Asteraceae) from Iran.

Mina Pakdelmoradlou, Hafize Yuca, Elif Beyza Özer, Bilge Aydın, Satuk Buğra Alkuyruk, Yusuf Gülşahin, Mehmet Karadayı, Gamze Göger, Gülnur Ekşi Bona, Mehmet Bona and 1 more

Abstract read
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Article in Protoplasma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mina PakdelmoradlouDepartment of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Türkiye.ORCID http://orcid.org/0009-0004-8108-6287
Hafize YucaDepartment of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Türkiye. hafize.yuca@atauni.edu.tr.ORCID http://orcid.org/0000-0002-0857-4776
Elif Beyza ÖzerDepartment of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Türkiye.ORCID http://orcid.org/0000-0001-7484-1126
Bilge AydınDepartment of Pharmacognosy, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan, Türkiye.ORCID http://orcid.org/0000-0002-7712-7259
Satuk Buğra AlkuyrukDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Atatürk University, Erzurum, Türkiye.ORCID http://orcid.org/0009-0008-8038-6615
Yusuf GülşahinDepartment of Biology, Faculty of Science, Atatürk University, Erzurum, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-3770-2116
Mehmet KaradayıDepartment of Biology, Faculty of Science, Atatürk University, Erzurum, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-2473-0409
Gamze GögerDepartment of Pharmacognosy, Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye.ORCID http://orcid.org/0000-0003-2978-5385
Gülnur Ekşi BonaDepartment of Pharmaceutical Botany, Faculty of Pharmacy, İstanbul University-Cerrahpaşa, İstanbul, Türkiye.ORCID http://orcid.org/0000-0002-6869-8703
Mehmet BonaDepartment of Biology, Faculty of Science, İstanbul University, İstanbul, Türkiye.ORCID http://orcid.org/0000-0003-1656-2641
Songül KarakayaFaculty of Pharmacy Department of Pharmaceutical Botany, Atatürk University, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-3268-721X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Onopordum acanthium L. (Asteraceae), a traditionally used medicinal plant, was investigated for its morphological, phytochemical, and biological properties in this comprehensive study. Methanolic and aqueous extracts were prepared from different parts of the plant (root, stem, leaf, flower, and fruit) and analyzed for their phenolic composition, antioxidant, antidiabetic, anticholinesterase, antimicrobial, and genotoxic activities. LC-MS/MS analysis revealed that chlorogenic acid was most abundant in the flower (3045.38 ng/mL) and root (728.53 ng/mL) aqueous extracts, while quinic acid reached 856.27 ng/mL in the root. Quercetin, apigenin, and luteolin were also detected at significant levels. The fruit methanol extract showed the highest total phenolic (100.78 ± 0.0015 µg GAE/mg), flavonoid (603.67 ± 0.0015 µg RE/mg), and tannin (186.22 ± 0.0015 µg TAE/mg) contents. Antioxidant assays demonstrated notable ABTS

Indexed as

PhytochemicalsPlant ExtractsAnti-Infective AgentsAntioxidantsCholinesterase InhibitorsHypoglycemic AgentsIranPhenolsAnti-Infective AgentsAntioxidantsCholinesterase InhibitorsHypoglycemic AgentsPhenolsPhytochemicalsPlant ExtractsAnticholinesteraseAntidiabeticAsteraceaeLC-MS/MSOnopordum acanthium

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.