Evidence map›Paper›PMID 41193816›Full record

ArticleNature2026

Secretome translation shaped by lysosomes and lunapark-marked ER junctions.

Heejun Choi, Ya-Cheng Liao, Young J Yoon, Jonathan Grimm, Nan Wang, Luke D Lavis, Robert H Singer, Jennifer Lippincott-Schwartz

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Fetuin-b Mediates Lipid Overload-Induced Hepatic Lipid Accumulation in Large Yellow Croaker (Larimichthys crocea).FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heejun ChoiJanelia Research Campus, HHMI, Ashburn, VA, USA.
Ya-Cheng LiaoColumbia University, New York, NY, USA.
Young J YoonAlbert Einstein College of Medicine, Bronx, NY, USA.
Jonathan GrimmJanelia Research Campus, HHMI, Ashburn, VA, USA.ORCID 0000-0003-0331-4200
Nan WangJanelia Research Campus, HHMI, Ashburn, VA, USA.ORCID 0000-0003-4630-5216
Luke D LavisJanelia Research Campus, HHMI, Ashburn, VA, USA.ORCID 0000-0002-0789-6343
Robert H SingerAlbert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-6725-0093
Jennifer Lippincott-SchwartzJanelia Research Campus, HHMI, Ashburn, VA, USA. lippincottschwartzj@janelia.hhmi.org.ORCID 0000-0002-8601-3501

Funding

Mechanism of MRNA Localization and Localized Translation in NeuronsR01NS083085 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Sulagna Das, Robert H Singer · 2013 to 2026
$9.0M
Dynamic visualization of polyribosomesR21MH120496 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI YOON, YOUNG JUN · 2019 to 2020
$459k
NIMH NIH HHS R21 MH120496NINDS NIH HHS R01 NS083085
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) is a highly interconnected membrane network that serves as a central site for protein synthesis and maturation

Indexed as

Endoplasmic ReticulumLysosomesMembrane ProteinsProtein BiosynthesisAmino AcidsEukaryotic Initiation Factor-2HeLa CellsHumansRibosomesRNA, MessengerSingle Molecule ImagingAmino AcidsEukaryotic Initiation Factor-2Membrane ProteinsRNA, Messenger

Identifiers

PMID41193816
PMCPMC12727531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.