ArticleNature2025
Anti-progestin therapy targets hallmarks of breast cancer risk.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- A multi-level charged micelle-based microneedle transdermal system for immunosuppressive tumor microenvironment regulation and synergistic therapy.Materials today. Bio · 2026Article
- Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy.MedComm · 2026Review
- Nuclear FGF2, androgen receptor and Wnt pathway activation define a targetable subset of antiprogestin-resistant luminal breast cancer.British journal of cancer · 2026Article
- Precision immunotherapy for breast cancer: from biomarkers to clinical practice.Cancer biology & medicine · 2026Article
- Progesterone receptors drive advanced breast cancer phenotypes including circulating tumor- and stem-like cell expansion in the context of ESR1 mutation.NPJ breast cancer · 2026Article
- Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance.NPJ breast cancer · 2026Review
- Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making.Frontiers in endocrinology · 2026Review
- Article
- Progesterone receptors drive advanced breast cancer phenotypes including circulating tumor- and stem-like cell expansion in the context ofbioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
36 authors.
Bruno M SimõesManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. bruno.simoes@manchester.ac.uk.ORCID 0000-0003-1253-6657
Robert PedleyManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-0801-7240
Curtis W McCloskeyPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-3481-2221
Matthew RobertsManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Austin D ReedDepartment of Pharmacology, University of Cambridge and Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.
Alecia-Jane TwiggerDepartment of Pharmacology, University of Cambridge and Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.ORCID 0000-0003-4361-817X
Pirashaanthy TharmapalanPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Amanda CarusoManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-3254-5764
Sara CabralManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0009-0007-5164-6935
Anthony J WilbyManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0009-0004-3165-9606
Hannah HarrisonManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-0054-8047
Yuxi ZhouManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Alice GreenhalghManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Suad A AlghamdiManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-8325-5994
Martina ForestieroManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Jesica Lopez-MuñozManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-5311-5579
Jasmin RocheManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Ren Jie TuiengDivision of Cell Matrix Biology & Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0001-9019-7342
Muhammad A KhanManchester Cell-Matrix Centre, University of Manchester, Manchester, UK.ORCID 0000-0003-4341-6551
Steven SquiresDivision of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0003-3681-1342
Susan M AstleyManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-2989-2765
Elaine F HarknessDivision of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0001-6625-7739
Angélica Santiago-GómezManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-2946-2669
Katherine SpenceManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-8137-165X
Jessica RitchieNightingale and Prevent Breast Cancer Centre, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
Susan PritchardNightingale and Prevent Breast Cancer Centre, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
Yit LimNightingale and Prevent Breast Cancer Centre, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.
Michael J SherrattDivision of Cell Matrix Biology & Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0003-4759-6617
Sebastiano AndòDepartment of Pharmacy, Health and Nutritional Sciences, Health Center, University of Calabria, Cosenza, Italy.
Anthony HowellManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
D Gareth EvansNightingale and Prevent Breast Cancer Centre, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.ORCID 0000-0002-8482-5784
Andrew P GilmoreManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Walid T KhaledDepartment of Pharmacology, University of Cambridge and Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.ORCID 0000-0001-9068-5776
Rama KhokhaPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Robert B ClarkeManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. robert.clarke@manchester.ac.uk.ORCID 0000-0001-5407-3123
Sacha J HowellManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. sacha.howell@nhs.net.ORCID 0000-0001-8141-6515
Funding
Wellcome Trust
Abstract
Breast cancer is the leading cause of cancer-related death in women worldwide
Indexed as
Breast NeoplasmsNorpregnadienesProgestinsAdultBreastCell ProliferationEpithelial CellsExtracellular MatrixFemaleHumansMagnetic Resonance ImagingPremenopauseReceptors, ProgesteroneStem CellsNorpregnadienesProgestinsReceptors, Progesteroneulipristal acetate
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.