Evidence map›Paper›PMID 41193803›Full record

ArticleNature2025

Two residues reprogram immunity receptors for nitrogen-fixing symbiosis.

Magdalini Tsitsikli, Bine Simonsen, Thi-Bich Luu, Maria M Larsen, Camilla G Andersen, Kira Gysel, Damiano Lironi, Christina Krönauer, Henriette Rübsam, Simon B Hansen and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Magdalini Tsitsikli *Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0009-0008-8753-529X
Bine Simonsen *Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-9197-9992
Thi-Bich Luu *Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-8148-6927
Maria M LarsenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Camilla G AndersenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Kira GyselDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-4245-9998
Damiano LironiDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Christina KrönauerDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Henriette RübsamDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Simon B HansenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-0843-3922
René BærentsenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Jesper Lundsgaard WulffDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Sarah Holt JohansenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Gülendam SezerDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Jens StougaardDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-9312-2685
Kasper Røjkjær AndersenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. kra@mbg.au.dk.ORCID 0000-0002-4415-8067
Simona RadutoiuDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. radutoiu@mbg.au.dk.ORCID 0000-0002-8841-1415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Receptor signalling determines cellular responses and is crucial for defining specific biological outcomes. In legume root cells, highly similar and structurally conserved chitin and Nod factor receptor kinases activate immune or symbiotic pathways, respectively, when chitinous ligands are perceived

Indexed as

LotusNitrogen FixationPlant ImmunityPlant ProteinsSymbiosisAmino Acid MotifsChitinHordeumPlant RootsProtein DomainsProtein Serine-Threonine KinasesSignal TransductionChitinPlant ProteinsProtein Serine-Threonine Kinases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.