ArticleNature2026
Lymph node environment drives FSP1 targetability in metastasizing melanoma.
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Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35citing papers in PubMed
–field-weighted citation impact
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Who cites it
35 citing papers in PubMed.
- Review
- Cuproptosis and ferroptosis: signal pathways, diseases and therapeutic targets.Signal transduction and targeted therapy · 2026Review
- Decreased FSP1 expression under chronic hypoxia sensitizes human macrophages towards ferroptosis.Redox biology · 2026Article
- Melanoma evolution in the lymph node shapes systemic outcomes.bioRxiv : the preprint server for biology · 2026Article
- Enhancement of Ferroptosis in Escape Variant Tumor Cells by IFNγ Derived from Antigen-Specific T Cells Controls Tumor with Heterogeneity.Cancer immunology research · 2026Article
- Article
- Ferroptotic propagation: from single-cell execution to tissue-scale death programs.Cell research · 2026Review
- Mechanisms underlying propagation of ferroptotic cell death.Nature cell biology · 2026Review
- Opposing roles of DGAT-mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity.The FEBS journal · 2026Article
- Ferroptosis as an approach to leverage cancer metabolism.Trends in cell biology · 2026Review
- CoQExperimental & molecular medicine · 2026Review
- Translating ferroptosis into oncology: challenges, opportunities and future directions.Nature reviews. Clinical oncology · 2026Review
- Redox-triggered USP18 confers cisplatin resistance in ovarian cancer by selectively activating a non-canonical FSP1-dependent ferroptosis escape pathway.Redox biology · 2026Article
- Hesperetin alleviates cerebral ischemia-reperfusion injury by suppressing neuronal ferroptosis.Scientific reports · 2026Article
- Diet-induced metabolic memory shapes CD8Nature immunology · 2026Article
- Review
- Fat bolsters tumours against ferroptosis.Nature cell biology · 2026Article
- When Pathways Converge: Iron, Lipid Peroxidation, and α-Synuclein in Ferroptosis-Driven Dopaminergic Neurodegeneration.Journal of neurochemistry · 2026Review
- GPX4 Inhibitor Resistance and Metastatic Features in Triple-Negative Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis.Nature structural & molecular biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors.
Mario PalmaDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0009-0007-9456-2096
Milena ChaufanDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Cort B BreuerDepartment of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0009-0009-2594-3754
Sebastian MüllerInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-3423-5364
Marie SabatierDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-7673-4842
Cameron S FraserDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-8180-5913
Krystina J SzyloDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0009-0007-0743-4812
Mahsa YavariDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Alanis CarmonaDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Mayher KaurDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Luiza Martins Nascentes MeloDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-5980-5220
Feyza CansizDepartment of Dermatology, University Hospital Essen & German Cancer Consortium (DKTK), Essen, Germany.
June Monge-LorenzoDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0009-0007-8943-759X
Midori FloresDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Eikan MishimaInstitute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0002-3706-2745
Toshitaka NakamuraInstitute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.
Bettina PronethInstitute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0002-4119-9437
Marcos LabradoDepartment of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0009-0008-3981-2651
Yanshan LiangDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Nicole CaytingDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Lan ZhengDepartment of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Tatiana CañequeInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-1110-0643
Ludovic ColombeauInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0001-5823-2603
Adam WahidaDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-8856-8834
José Pedro Friedmann AngeliRudolf Virchow Center for Integrative and Translational Bioimaging, Chair of Translational Cell Biology, University of Würzburg, Würzburg, Germany.ORCID 0000-0001-7706-1379
Alpaslan TasdoganDepartment of Dermatology, University Hospital Essen & German Cancer Consortium (DKTK), Essen, Germany.ORCID 0000-0003-2543-852X
Sheng HuiDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Raphaël RodriguezInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0001-7668-446X
Marcus ConradInstitute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0003-1140-5612
Nathan E Reticker-FlynnDepartment of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-9963-039X
Jessalyn M UbellackerDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA. jubellacker@hsph.harvard.edu.ORCID 0000-0002-7855-9125
Funding
A modular cell therapy platform for controlling immunological toleranceDP2AI177915 · NIAID · STANFORD UNIVERSITY · PI Nathan Edward Reticker-Flynn · 2023 to 2026
$1.9MPreventing Melanoma Metastasis by Targeting Lipid Vulnerabilities in LymphR01CA282202 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Jessalyn Ubellacker · 2024 to 2026
$1.3MTraining Program in Molecular MetabolismT32DK128781 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sudha B Biddinger, GOKHAN S HOTAMISLIGIL · 2021 to 2026
$1.1MFluxomics Studies of the Effect of Diet Composition on Energy MetabolismR56DK140139 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI HUI, SHENG · 2024 to 2024
$507kInvestigating evolutionary antagonism between tumors and lymphocytesF31CA301857 · NCI · STANFORD UNIVERSITY · PI Cort Breuer · 2025 to 2026
$94kNCI NIH HHS F31 CA301857NCI NIH HHS R01 CA282202NIAID NIH HHS DP2 AI177915NIDDK NIH HHS R56 DK140139NIDDK NIH HHS T32 DK128781
Abstract
Ferroptosis has emerged as an actionable target to eliminate therapy-resistant and metastatic cancers
Indexed as
Lymphatic MetastasisLymph NodesMelanomaTumor MicroenvironmentAnimalsApoptosis Regulatory ProteinsCell Line, TumorFemaleFerroptosisGlutathioneHumansLysosomesMaleMiceOxidoreductasesPhospholipid Hydroperoxide Glutathione PeroxidaseApoptosis Regulatory Proteinsferroptosis suppressor protein 1, mouseGlutathioneglutathione peroxidase 4, mouseOxidoreductasesPhospholipid Hydroperoxide Glutathione PeroxidaseProteasome Endopeptidase Complex
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.