Evidence map›Paper›PMID 41193793›Full record

ArticleEuropean journal of pediatrics2025

Lung ultrasound aeration scores and their utility in predicting success of weaning off respiratory support in preterm neonates-A prospective cohort study.

Ahmed Elkordy, Ahmed Abuelnour, Andrea De La Hoz, Michael R Miller, Jagraj Brar, Sriya Roychaudhuri, Renjini Lalitha

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Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ahmed ElkordyDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Western University, London, ON, Canada.
Ahmed AbuelnourDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Western University, London, ON, Canada.
Andrea De La HozDepartment of Pediatrics, London Health Sciences Centre Research Institute (LHSCRI), London, ON, Canada.
Michael R MillerChildren's Health Research Institute, London, ON, Canada.
Jagraj BrarDepartment of Pediatrics, Division of Pediatric Intensive Care, Western University, London, ON, Canada.
Sriya RoychaudhuriDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Western University, London, ON, Canada. dr.sriyarc@gmail.com.
Renjini LalithaDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Western University, London, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aims to determine the utility of lung ultrasound aeration scoring (LUS Aeration Scores) in predicting successful weaning off nasal continuous positive airway pressure (nCPAP) in preterm neonates. This was a prospective cohort study conducted in a tertiary neonatal unit between September 2022 and September 2023. Preterm neonates born < 33 weeks gestational age (GA) needing any respiratory pressure support after birth were included. LUS was performed at two time points; LUS1 at 30

conclusionLUS is a reliable tool to assess readiness for nCPAP trial off. A pre-trial off LUS Aeration Score ≤ 8 was associated with higher successful weaning off nCPAP after 32 weeks GA. WHAT IS KNOWN: • Lung ultrasound is a useful bedside tool to assess various neonatal respiratory disorders and for prediction of need for respiratory support and surfactant therapy. WHAT IS NEW: • This study presents lung ultrasound as a precision-based tool to assess pulmonary readiness for weaning from non-invasive respiratory support in preterm infants. • Lung ultrasound aeration score at the time of trial-off reliably predicted successful weaning, independent of gestational age at birth or operator expertise.

Indexed as

Continuous Positive Airway PressureLungRespiratory Distress Syndrome, NewbornVentilator WeaningFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMalePredictive Value of TestsProspective StudiesReproducibility of ResultsROC CurveUltrasonographyLung ultrasoundPredictive powerPreterm neonatesWeaning off respiratory pressure support

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.