ArticleScientific reports2025
Adipose gene expression related to body condition score and individual variations in hospitalized cats.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for various diseases. The prevalence of obesity is increasing in cats. The present study aimed to characterize adipose gene expression to obtain basic information for obesity prevention in feline adipose tissues. Visceral fat, subcutaneous fat, or both fat depots were collected from 81 hospitalized cats. The multivariate analysis of covariance revealed that sex and IGF-1 were involved in regulating body condition score (BCS), showing adiposity in both fat depots. BCS was positively and negatively regulated by expression levels of inflammation-related genes in visceral fat, respectively. In addition, subcutaneous Lep expression positively regulated BCS. Positive correlations between gene expression levels were generally detected within the same fat depot, whereas expression levels of genes in visceral fat were less related to those in subcutaneous fat, except for the same gene. Expression levels of Ucp1 were most variable among individuals in visceral fat but not in subcutaneous fat. The extent of individual variability on expression levels in cats was similar to that in the previous results using dogs. Genes related to mitochondrial respiration and uncoupling were relatively variable among individuals. The present study suggests that feline energy metabolism in adipose tissues is finely tuned in a fat depot-dependent manner. In addition, genes related to mitochondrial respiration and uncoupling may be a target for the control of systemic energy status because they can be potentially regulated by every individual.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.