Evidence map›Paper›PMID 41193533›Full record

ArticleScientific reports2025

Using item response theory as a methodology to impute categorical missing values.

Adrienne Kline, Yuan Luo

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Adrienne KlineDepartment of Surgery, Northwestern University, Chicago, USA. adrienne.kline@northwestern.edu.
Yuan LuoDepartment of Preventative Medicine, Northwestern University, Chicago, USA. yuan.luo@northwestern.edu.

Funding

CRITICAL: Collaborative Resource for Intensive care Translational science, Informatics, Comprehensive Analytics, and LearningU01TR003528 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIMINO, JAMES J, LUO, YUAN · 2021 to 2024
$4.9M
Modeling the Incompleteness and Biases of Health DataR01LM013337 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2020 to 2023
$1.3M
NCATS NIH HHS U01 TR003528NIH HHS U01TR003528NLM NIH HHS R01 LM013337
6 · The paper itself

Abstract

Most datasets suffer from partial or complete missing values, which has downstream limitations on the available models on which to test the data and on any statistical inferences that can be made from the data. Several imputation techniques have been designed to replace missing data with stand in values. The various approaches have implications for calculating clinical scores, model building and model testing. The work showcased here supports using an Item Response Theory (IRT) based approach for categorical imputation, comparing it against several methodologies currently used in the machine learning field including k-nearest neighbors (kNN), multiple imputed chained equations (MICE) and Amazon Web Services (AWS) deep learning method, DataWig. Analyses comparing these techniques were performed on three different datasets that represented ordinal, nominal and binary categories. The data were modified so that they also varied on both the proportion of data missing and the systematization of the missing data. Two different assessments of performance were conducted: accuracy in reproducing the missing values, and predictive performance using the imputed data. Results demonstrated that the proposed method, Item Response Theory for categorical imputation, fared quite well compared to currently used multiple imputation methods, outperforming several of them in many conditions. Given the theoretical basis for the approach, and the unique generation of probabilistic terms for determining category belonging for missing cells, IRT for categorical imputation offers a viable alternative to current approaches.

Indexed as

Categorical imputationItem response theory (IRT)Missing at random (MAR)Missing completely at random (MCAR)

Identifiers

PMID41193533
PMCPMC12589431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.