SynthesisThe Journal of international medical research2025
Isolated cardiac sarcoidosis: A systematic review.
Synthesis in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Diagnostic challenges in isolated cardiac sarcoidosis.ESC heart failure · 2026Review
- Unmasking Cardiac Sarcoidosis: Integrating Multimodal Imaging with Histochemical and Ultrastructural Analysis.International journal of molecular sciences · 2026Review
- Latest Management of Cardiac Sarcoidosis: A Comprehensive Review.Cardiology research and practice · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundIsolated cardiac sarcoidosis is a distinct entity of sarcoidosis characterized by disease confined exclusively to the heart, without involvement of other organs. While cardiac sarcoidosis can lead to severe complications such as arrhythmias and heart failure, isolated cardiac sarcoidosis remains understudied, and no systematic review has previously addressed this condition.Key findings: A systematic review of the literature from 1978 to 2025 identified 14 relevant studies, primarily case series. Isolated cardiac sarcoidosis affects both sexes equally, with most patients aged 55-65 years. Compared with multi-organ cardiac sarcoidosis, isolated cardiac sarcoidosis is associated with lower left ventricular ejection fraction and poorer survival. Variability in diagnostic criteria and potential selection bias were key limitations.ConclusionIsolated cardiac sarcoidosis is a distinct and severe clinical entity with limited available data. Its poorer prognosis underscores the need for specific diagnostic and management guidelines. Future multicenter studies are essential to improve understanding and care for patients with this condition.
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Registered trials
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