ArticleInternational journal of spine surgery2025
Metabolic Syndrome as a Risk Factor for Postoperative Complication in Patients Undergoing Spine Surgery: A Systematic Review and Meta-Analysis of More Than 3 Million Cases.
Article in International journal of spine surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIncluding conditions like obesity, diabetes, hypertension, and dyslipidemia, metabolic syndrome disrupts metabolic homeostasis and impairs recovery, increasing the risk of surgical complications. This study evaluates the impact of metabolic syndrome on spine surgery outcomes, addressing inconsistencies in the existing literature.
methodsFour databases were searched until December 2024 for studies comparing the postoperative complication rates of spine surgeries between patients with and without metabolic syndrome. Following deduplication, 2 authors independently reviewed the studies. For each included study, demographics and incidence rates of postoperative complications were extracted separately by 2 authors. Data analysis was performed using R.
resultsAfter deduplication, 115 studies were evaluated for inclusion in our study. Following the review of full texts, 11 studies were included. No significant differences were found between patients with and without metabolic syndrome in terms of mortality and nonhome discharge, pulmonary thromboendarterectomy, pneumonia, and sepsis (
conclusionsMetabolic syndrome might significantly increase the risk of some postoperative complications in spine surgery patients. These findings highlight the need for personalized preoperative planning and management strategies to mitigate surgery risks. CLINICAL RELEVANCE: Identifying and optimizing metabolic syndrome components before surgery may improve patient outcomes and reduce complication rates. LEVEL OF EVIDENCE: 2:
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.