Evidence map›Paper›PMID 41193209›Full record

ArticleBMJ open2025

Maddison L Mellow, Henry T Blake, Ty Ferguson, Bethany Robins, Dorothea Dumuid, Timothy Olds, Tyman E Stanford, Kate Laver, Hannah Keage, Alison Coates and 8 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06291909 (Small Steps Towards Personalized Dementia Prevention), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06291909 naactive not recruitingnot on this map

Small Steps Towards Personalized Dementia Prevention: Implementation and Evaluation of a Personalized, Technology-assisted Physical Behaviour Intervention

TypeinterventionalSponsorUniversity of South AustraliaRan2024 to 2027Enrolled88ConditionsDementia, Alzheimer DiseaseArmsSmall Steps Program, Comparator Program
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cognitive Engagement and Dementia Risk: A Dose-Response Comparison of Nursing Home and Community Residents.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maddison L MellowAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-0514-8261
Henry T BlakeAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0001-9903-9287
Ty FergusonAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Bethany RobinsAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Dorothea DumuidAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0003-3057-0963
Timothy OldsAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Tyman E StanfordAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Kate LaverCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0003-0259-2209
Hannah KeageJustice and Society, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-6814-4997
Alison CoatesAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0003-1031-2545
Alexandra T WadeCollege of Education, Psychology and Social Work, Flinders University, Adelaide, South Australia, Australia.
Michelle RogersAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Aaron DavisAustralian Research Centre for Interactive and Virtual Environments, UniSA Creative, University of South Australia, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-1477-7406
Lui Di VenutoCity of Onkaparinga, Noarlunga Centre, South Australia, Australia.
Emma TregowethAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Catherine YandellAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia.
Barbara TainshACH Group Inc, Mile End, South Australia, Australia.
Ashleigh E SmithAlliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, South Australia, Australia ashleigh.smith@unisa.edu.au.ORCID http://orcid.org/0000-0001-6316-2259

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAddressing physical inactivity is a promising dementia risk reduction strategy due to its direct benefits for brain health, and indirect benefits for other modifiable dementia risk factors. A potential limitation of previous interventions is that they often overlook how increasing physical activity affects other behaviours throughout the 24-hour day, such as sleep and sedentary behaviour, which are also important for brain health. Further, interventions are rarely tailored to the individual, considering their needs, preferences and constraints that may serve as barriers or facilitators to behaviour change. The current phase I randomised controlled trial, METHODS AND ANALYSIS: Participants aged ≥65 years from Adelaide, South Australia will be recruited and randomised to either the Extended or Condensed programme. During the first 12 weeks, participants in the Extended programme will use a tailored website to set personalised weekly goals to move towards their 'optimal' 24-hour day for brain health, facilitated by weekly website 'check-ins' and weekly phone calls with a research staff member. Participants randomised to the Condensed programme will have access to the website educational resources only but will not undergo personalised goal setting or telephone calls. Following the introductory phase (first 12 weeks), phone calls will be gradually withdrawn for the Extended programme. Primary (feasibility and acceptability) and secondary outcomes (changes in time use, cognitive function and behaviour change metrics) will be assessed 12, 24 and 36 weeks after the beginning of the intervention. ETHICS AND DISSEMINATION: Ethics approval has been obtained from the University of South Australia's Human Research Ethics Committee (205989). Study findings will be disseminated through peer-reviewed journal articles, conference presentations, media releases and community engagement. TRIAL REGISTRATION NUMBER: NCT06291909).

Indexed as

DementiaExerciseRisk Reduction BehaviorSedentary BehaviorAgedFemaleHumansIndependent LivingMaleRandomized Controlled Trials as TopicSouth AustraliaAgingCognitionDigital TechnologyExerciseRandomized Controlled Trial

Identifiers

PMID41193209
PMCPMC12588037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.