Evidence map›Paper›PMID 41193017›Full record

Observational studyThe western journal of emergency medicine2025

Untreated Hypertension and Diabetes in the Chest Pain Observation Unit.

Benjamin T Hutchison, Nicklaus P Ashburn, Anna C Snavely, Michael D Shapiro, Michael A Chado, Alexander P Ambrosini, Amir A Biglari, Harris A Cannon, Marissa J Millard, Alexa G Dameron and 1 more

Abstract readObservational Study
In one paragraph

Observational study in The western journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benjamin T HutchisonWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Nicklaus P AshburnWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Anna C SnavelyWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Michael D ShapiroWake Forest University School of Medicine, Section on Cardiovascular Medicine, Department of Internal Medicine, Wake Forest University, Winston-Salem, North Carolina.
Michael A ChadoOhio State University, Department of Emergency Medicine, Columbus, Ohio.
Alexander P AmbrosiniYale School of Medicine, Department of Internal Medicine, New Haven, Connecticut.
Amir A BiglariWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Harris A CannonWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Marissa J MillardWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Alexa G DameronWake Forest University School of Medicine, Department of Emergency Medicine, Wake Forest University, Winston-Salem, North Carolina.
Simon A MahlerWake Forest University School of Medicine, Department of Implementation Science, Wake Forest University, Winston-Salem, North Carolina.

Funding

Initiating Preventive Care for Hyperlipidemia in the Emergency Department: The EMERALD TrialK23HL169929 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicklaus P Ashburn · 2024 to 2026
$468k
AHRQ HHS R01 HS029017AHRQ HHS R21 HS029234NHLBI NIH HHS K23 HL169929
6 · The paper itself

Abstract

introductionHypertension and diabetes are common cardiovascular disease risk factors among emergency department observation unit (EDOU) patients evaluated for acute coronary syndrome (ACS). Our primary aim was to determine rates of untreated hypertension and diabetes in the EDOU. Our secondary aim was to identify rates of glycemic control assessment among patients with diabetes.

methodsWe conducted a retrospective, observational cohort study of patients ≥ 18 years old evaluated for ACS in a tertiary care center EDOU from March 3, 2019-February 28, 2020. Known diagnoses prior to EDOU encounter and new outpatient diagnoses within one year for hypertension and diabetes were identified by health record data. We defined untreated hypertension and diabetes as no antihypertensive or antihyperglycemic prescriptions or diabetes counseling within one year. We calculated treatment rates with exact 95% confidence intervals (CI). Multivariable logistic regression adjusting for age, sex, and race compared treatment rates among men vs women and White vs non-White patients. Rates of glycemic control assessment were defined by the proportion of patients with known diabetes who received hemoglobin A1c (HbA1c) measurement within one year.

resultsAmong 649 EDOU patients, 59.5% (386/649) were female and 43.8% (284/649) were non-White with a mean age of 59 ± 12 years. Of these, 76.9% (499/649) had known hypertension and 31.3% (203/649) had known diabetes. Within one year, 3.1% (20/649) had newly diagnosed hypertension and 3.2% (21/649) had newly diagnosed diabetes. Among those with known or newly diagnosed hypertension, untreated hypertension occurred in 36.4% (189/519; 95% CI 32.3 - 40.7). Hypertension treatment rates were similar in men vs women (aOR [adjusted odds ratio] 0.82, 95% CI 0.57 - 1.19) and White vs non-White patients (aOR 0.95, 95% CI 0.66 - 1.38). Among those with known or newly diagnosed diabetes, untreated diabetes occurred in 25.0% (56/224; 95% CI 18.5 - 31.2). Diabetes treatment rates were similar in men vs women (aOR 1.41, 95% CI 0.72 - 2.74) and White vs. non-White patients (aOR 1.05, 95% CI 0.56 - 1.97). At one year, just 32.0% (65/203) of patients with diabetes had HbA1c testing.

conclusionGiven that many patients evaluated for acute coronary syndrome in the ED observation unit do not receive treatment for hypertension and diabetes within one year of presentation, clinicians should consider initiating EDOU-based preventive cardiovascular care for these conditions.

Indexed as

Acute Coronary SyndromeChest PainClinical Observation UnitsDiabetes MellitusHypertensionAgedEmergency Service, HospitalFemaleGlycated HemoglobinHumansMaleMiddle AgedRetrospective StudiesRisk FactorsGlycated Hemoglobin

Identifiers

PMID41193017
PMCPMC12591649

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.