Evidence map›Paper›PMID 41193014›Full record

Observational studyThe western journal of emergency medicine2025

Emergency Department Management of Acute Heatstroke: A Retrospective Analysis from Phoenix, Arizona.

Jeffrey R Stowell, Paul Pugsley, Megan McElhinny, Geoffrey Comp, Jacquelyn Pearlmutter, Murtaza Akhter, David Sklar

Abstract readObservational Study
In one paragraph

Observational study in The western journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey R StowellValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
Paul PugsleyValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
Megan McElhinnyValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
Geoffrey CompValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
Jacquelyn PearlmutterPenn State Health Milton S. Hershey Medical Center, Department of Emergency Medicine, Hershey, Pennsylvania.
Murtaza AkhterValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
David SklarValleywise Health, Department of Emergency Medicine, Phoenix, Arizona.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe global incidence and severity of severe heat illness is on the rise. The increasing number of summer heatwaves in Phoenix, Arizona, gave us a distinctive opportunity to better understand the impact on the clinical presentation and management of acute heatstroke. Our primary objective in this study was to describe the prehospital and emergency department (ED) clinical presentation, treatment, and outcomes of patients with acute heatstroke at a single hospital system during the summers of 2021 and 2022 in Phoenix.

methodsThis was a descriptive, retrospective observational study of heatstroke-associated adult ED presentations occurring from June 1 - August 31, 2021 and June 1 - August 31, 2022, to a single hospital system in Maricopa County.

resultsWe identified 60 ED heatstroke encounters. The median environmental daily maximum (Tmax) and minimum (Tmin) were 106.0° Fahrenheit (interquartile range [IQR]) 102.0 - 109.0°F) and 84.0°F (IQR 79.0 - 88.0°F), respectively. The patients were commonly male (42, 70.0%, 95% CI 56.8 - 81.2%), White (26, 43.3%, 95% CI 30.6 - 56.8%), middle-aged (mean 52.7 years, 95% CI 48.4 - 56.9), Medicaid-insured (37, 61.7%, 95% CI 48.2 - 73.9%), and presenting via emergency medical services (60, 100%). Patients were commonly of high acuity (median Emergency Severity Index 1, IQR 1.0 - 2.0), and intubated (45, 75.0%, 95% CI 62.1-85.3%). Forty-seven (78.3%, 95% CI 65.8 - 87.9%) patients were found unresponsive outside with associated substance use (methamphetamines 22, 46.8%, 95% CI 32.1 - 61.9%; and fentanyl 14, 29.8%, 95% CI 17.3 - 44.9%). The average patient Tmax at ED presentation was 41.9°C (IQR 41.1 - 42.2). Forty-one patients (68.3%, 95% CI 55.0 - 79.7%) survived to hospital discharge or transfer, of whom 32 (82.1%, 95% CI 66.5 - 92.5%) were neurologically intact.

conclusionDuring the summers of 2021 and 2022, a significant number of heatstroke presentations were treated in a single healthcare system in Maricopa County, Arizona. A substantial number were successfully treated with cold water immersion and discharged neurologically intact. In this urban population, extreme weather exposure and associated substance use appeared to play significant roles.

Indexed as

Emergency Service, HospitalHeat StrokeAdultAgedArizonaFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID41193014
PMCPMC12591635

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.