Evidence map›Paper›PMID 41192959›Full record

ArticleBritish journal of sports medicine2026

Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium.

Noortje Riedstra, Fleur Boel, Michiel Ma van Buuren, Harbeer Ahedi, Vahid Arbabi, Nigel K Arden, Sara J Baart, Sita M A Bierma-Zeinstra, Flavia Cicutini, Timothy Cootes and 18 more

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Article in British journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

28 authors.

Noortje RiedstraOrthopedics and Sports Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands noortjesophie@gmail.com.ORCID http://orcid.org/0000-0003-0786-0348
Fleur BoelOrthopedics and Sports Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.ORCID http://orcid.org/0000-0002-0421-9478
Michiel Ma van BuurenOrthopedics and Sports Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.
Harbeer AhediUniversity of Tasmania Menzies Institute for Medical Research, Hobart, Tasmania, Australia.
Vahid ArbabiUniversity Medical Centre Utrecht, Utrecht, The Netherlands.
Nigel K ArdenNDORMS, University of Oxford, Oxford, UK.
Sara J BaartDepartment of Biostatistics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Sita M A Bierma-ZeinstraDepartment of General Practice, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Flavia CicutiniMonash University, Melbourne, Victoria, Australia.
Timothy CootesManchester University, North Manchester, Indiana, USA.
Kay M CrossleyLa Trobe University-Bundoora Campus, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0001-5892-129X
David T FelsonClinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA.
Willem-Paul GielisUniversity Medical Centre Utrecht, Utrecht, The Netherlands.
Joshua J HeereyLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-8691-1830
Graeme JonesMenzies Research Institute Tasmania, Hobart, Tasmania, Australia.
Stefan KluzekDepartment of Sports Medicine, University of Nottingham, Nottingham, UK.
Nancy E LaneDivision of Rheumatology, Allergy and Clinical Immunology, Department of Medicine, University of California, Davis, California, USA.
Claudia LindnerUniversity of Manchester-The Victoria University of Manchester Campus, Manchester, UK.
John A LynchDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Joyce van MeursErasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.
Andrea Britt MoslerLa Trobe Sport and Exercise Medicine Research Centre, La Trobe University-Bundoora Campus, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-7353-2583
Amanda E NelsonDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Michael C NevittUniversity of California San Francisco, San Francisco, California, USA.
Edwin H G OeiErasmus Universiteit Rotterdam, Rotterdam, The Netherlands.
Jos RunhaarDepartment of General Practice, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Jinchi TangOrthopedics and Sports Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.ORCID http://orcid.org/0000-0002-1028-5922
Harrie WeinansDepartment of Orthopaedics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Rintje AgricolaOrthopedics and Sports Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.ORCID http://orcid.org/0000-0002-0645-093X

Funding

Project 3: Intraarticular MineralizationU19AG076471 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TUHINA NEOGI · 2023 to 2026
$49.0M
Study of Osteoporotic FracturesR01AG005407 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CUMMINGS, STEVEN RON, YAFFE, KRISTINE · 1986 to 2016
$23.2M
Multicenter Osteoarthritis Study (MOST) Second RenewalU01AG019069 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEVITT, MICHAEL C · 2001 to 2020
$21.7M
Multicenter Osteoarthritis Study (MOST) Second Renewal: Iowa Clinical CenterU01AG018832 · NIA · UNIVERSITY OF IOWA · PI SEGAL, NEIL A, TORNER, JAMES C · 2001 to 2020
$14.1M
Multicenter Osteoarthritis Study (MOST) Second Renewal - Boston UniversityU01AG018820 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2019
$13.6M
Multicenter Osteoarthritis Study (MOST) Second Renewal - UAB Clinical CenterU01AG018947 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 2001 to 2020
$13.2M
Study of Osteoporotic FracturesR01AG005394 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ENSRUD, KRISTINE · 1986 to 2015
$6.1M
UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
NIAMS Multidisciplinary Clinical Research CenterP60AR064166 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHWARTZ, TODD A · 2013 to 2017
$5.8M
STUDY OF OSTEOPOROTIC FRACTURES: VERTEBRAL FRACTURESR01AR035583 · NIAMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 1986 to 2005
$3.2M
Study of Osteoporotic Fractures (SOF)R01AG027574 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 2006 to 2015
$2.6M
NCCDPHP CDC HHS U01 DP003206NCCDPHP CDC HHS U01 DP006266NIAMS NIH HHS P30 AR072580NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465NIAMS NIH HHS P60 AR064166NIAMS NIH HHS R01 AR035582NIAMS NIH HHS R01 AR035583NIAMS NIH HHS R01 AR035584NIA NIH HHS R01 AG005394NIA NIH HHS R01 AG005407NIA NIH HHS R01 AG027574NIA NIH HHS R01 AG027576NIA NIH HHS U01 AG018820NIA NIH HHS U01 AG018832NIA NIH HHS U01 AG018947NIA NIH HHS U01 AG019069NIA NIH HHS U19 AG076471Wellcome Trust 223267
6 · The paper itself

Abstract

objectiveTo assess the relationship between pincer morphology and incident radiographic hip osteoarthritis (RHOA) and study-specific subgroups.

methodsHips completely free of RHOA at baseline and with follow-up within 4-8 years were drawn from the World COACH consortium. The lateral centre edge angle (LCEA) was calculated uniformly on all baseline radiographs. Moderate pincer morphology was defined as an LCEA ≥40°, and severe pincer morphology as an LCEA ≥45° in sensitivity analyses. The primary outcome was incident RHOA defined by a harmonised OA score. A logistic regression model with generalised mixed effects with three levels (within-cohort, within-person and within-hip side correlation) adjusted for age, biological sex and body mass index (BMI) was employed. Descriptive statistics are reported for age, biological sex and BMI.

results18 935 hips from nine cohorts were included. 4894 hips (25.8%) had moderate pincer morphology. Within 8 years (mean 6.0±1.7 years), 352 hips (1.9%) developed RHOA. Moderate pincer morphology was not associated with RHOA (OR 1.15 (0.92-1.51)), whereas severe pincer morphology was significantly associated (OR 1.50 95% CI 1.05 to 2.15). Moderate pincer morphology in groups aged 40-50 (RR 2.67, 95% CI 1.43 to 4.95) and BMI ≥25 (RR 1.23 95% CI 0.98 to 1.71) had a higher risk compared with non-pincer hips. Women (RR 1.20 95% CI 0.93 to 1.56) with pincer morphology may be more at risk than men (RR 0.95 95% CI 0.57 to 1.58).

conclusionThe odds of developing RHOA within 8 years for hips with severe pincer morphology are 1.5 times higher than pincer-free hips, whereas moderate pincer morphology was not significantly associated with RHOA. Further research is necessary to uncover high risk subgroups of pincer morphology.

Indexed as

Hip JointOsteoarthritis, HipAdultAgedFemaleHumansIncidenceMaleMiddle AgedProspective StudiesRadiographyRisk FactorsEpidemiologyHipRisk factor

Identifiers

PMID41192959
PMCPMC7618612

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