Evidence map›Paper›PMID 41192909›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Malignancy-associated Multicentric Reticulohistocytosis Mimicking Dermatomyositis-like Features, with a Significant Ultrasound Finding.

Hirotake Inomata, Shinya Asatani, Natsumi Ikumi, Masashi Uchikawa, Kiichi Sugito, Masahiro Nishihara, Kumiko Akiya, Miho Oshima, Noboru Kitamura, Hideki Nakamura

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Hirotake InomataDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Shinya AsataniDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Natsumi IkumiDivision of Cutaneous Science, Department of Dermatology, Nihon University School of Medicine, Japan.
Masashi UchikawaDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Kiichi SugitoDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Masahiro NishiharaDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Kumiko AkiyaDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Miho OshimaDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Noboru KitamuraDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.
Hideki NakamuraDivision of Hematology and Rheumatology, School of Medicine, Nihon University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicentric reticulohistocytosis (MRH) is a rare systemic non-Langerhans cell histiocytosis characterized by destructive polyarthritis and nodular skin lesions, often associated with malignancy. We present the case of a 74-year-old Japanese man initially suspected of having dermatomyositis due to polyarthritis, typical skin manifestations, and laboratory findings. Malignancy screening revealed invasive bladder cancer, which necessitated surgery and chemotherapy. Although the skin symptoms improved, aggressive joint destruction persisted, and histopathological analyses confirmed MRH. Remarkably, ultrasonography revealed significant inflammation and tendon involvement, highlighting its diagnostic utility. This case emphasizes the challenge of distinguishing MRH from autoimmune diseases and the critical role of ultrasound in capturing destructive joint damage.

Indexed as

DermatomyositisHistiocytosis, Non-Langerhans-CellUrinary Bladder NeoplasmsAgedDiagnosis, DifferentialHumansMaleUltrasonographybladder cancerdermatomyositismulticentric reticulohistocytosis

Identifiers

PMID41192909
PMCPMC13349477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.