Evidence map›Paper›PMID 41192823›Full record

ArticleACS nano2025

Accurate Single-Nanoparticle Sizing down to 3 nm with an Optofluidic Microcavity.

Shalom Palkhivala, Larissa Kohler, Christian Ritschel, Claus Feldmann, David Hunger

Abstract read
In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shalom PalkhivalaKarlsruher Institut für Technologie, Physikalisches Institut, Wolfgang-Gaede-Str. 1, Karlsruhe 76131, Germany.ORCID 0009-0008-5261-0552
Larissa KohlerKarlsruher Institut für Technologie, Physikalisches Institut, Wolfgang-Gaede-Str. 1, Karlsruhe 76131, Germany.
Christian RitschelKarlsruher Institut für Technologie, Institut für Anorganische Chemie, Engesserstr. 15, Karlsruhe 76131, Germany.
Claus FeldmannKarlsruher Institut für Technologie, Institut für Anorganische Chemie, Engesserstr. 15, Karlsruhe 76131, Germany.ORCID 0000-0003-2426-9461
David HungerKarlsruher Institut für Technologie, Physikalisches Institut, Wolfgang-Gaede-Str. 1, Karlsruhe 76131, Germany.ORCID 0000-0001-6156-6145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles are ubiquitous, and methods that reveal insights into single-particle properties are highly desired to enable their advanced characterization. Techniques that achieve label-free single-nanoparticle detection often lack bandwidth or do not provide quantitative information. Here, we present a cavity-based dispersive sensing method that achieves a high bandwidth to capture all relevant time scales of translational diffusion and a sensitivity to detect and size single particles with diameters down to 3 nm. We develop an analytical model describing the autocorrelation function for particle diffusion in a standing-wave sensing geometry and propose a method to address the challenges posed by the transient nature of single-particle signals. With this, we achieve quantitative particle sizing with high precision and accuracy and provide an important tool to analyze single-particle diffusion.

Indexed as

autocorrelationBrownian motiongold nanoparticlesoptical microcavitysingle-particle detectionsizing

Identifiers

PMID41192823
PMCPMC12632166

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.