ArticlePediatrics2025
Decreasing Exposure to Mechanical Ventilation in Extremely Preterm Infants.
Article in Pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Lung ultrasound evolution after interventional closure of the ductus in preterm babies.European journal of pediatrics · 2026Observational
- Observational
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectivesProvider variability in mechanical ventilation weaning practices may result in prolonged invasive ventilation exposure that may contribute to the development of bronchopulmonary dysplasia (BPD) in extremely preterm infants. Our SMART aim was to reduce the proportion of infants born between 24 and 28 6/7 weeks' gestation exposed to invasive ventilation for more than 7 days by 25% within 12 months.
methodsThis was a single-center quality improvement initiative at The University of Alabama at Birmingham conducted between January 2021 and March 2023. Interventions to reduce mechanical ventilation exposure included the following: (1) establishing a consensus for invasive ventilation exposure including intubation, extubation, and reintubation, (2) development of a bedside weaning readiness tool to facilitate permissive hypercapnia, (3) empowerment of respiratory therapist facilitated weaning, and (4) the creation of a ventilation dashboard. All measures were analyzed using statistical process control charts.
resultsThe initiative included 340 infants with a median gestational age of 26 6/7 weeks (IQR, 25-28) and birth weight of 842 g (IQR, 686-1011). The baseline proportion of infants invasively ventilated for more than 7 days at baseline was 44%, which decreased to 25% following implementation of the bedside weaning readiness and communication tool. Special cause variation was also observed for rates of BPD or death, which decreased from a baseline of 55% to 40%.
conclusionsIn infants between 24 and 28 6/7 weeks' gestation, systematic ventilator weaning was associated with a decrease in infants invasively ventilated for more than 7 days and a decrease in BPD or death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.