Evidence map›Paper›PMID 41191720›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2025

Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient.

Gilberto Gambero Gaspar, Ludmilla Tonani, Patrícia Helena Grizante Barião, Otávio Guilherme Gonçalves de Almeida, Roberto Martinez, Marcia Regina von Zeska Kress

Abstract readCase Reports
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gilberto Gambero GasparUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Medicina Social, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-6804-454X
Ludmilla TonaniUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6892-8962
Patrícia Helena Grizante BariãoUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1335-3975
Otávio Guilherme Gonçalves de AlmeidaUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9271-1752
Roberto MartinezUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6906-7981
Marcia Regina von Zeska KressUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1239-7722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarocladium spp. are filamentous fungi commonly associated with plant diseases and only rarely cause hyalohyphomycosis in humans. Immunosuppressed patients are at risk for this infection, which typically presents with skin and subcutaneous lesions that may eventually disseminate to internal organs. This study reports a case of a man in intensive care following SARS-CoV-2 infection. During hospitalization, he developed neutropenia, persistent fever, and a cavitary lung lesion. Sarocladium spp. was isolated from blood cultures, and the patient was treated with voriconazole, leading to a successful cure. To our knowledge, this is the first reported case of Sarocladium implicatum infection in a COVID-19 patient, underscoring the importance of monitoring opportunistic fungal infections in immunocompromised individuals, particularly during epidemics and pandemics.

Indexed as

COVID-19HypocrealesOpportunistic InfectionsAntifungal AgentsHumansImmunocompromised HostMaleSARS-CoV-2VoriconazoleAntifungal AgentsVoriconazole

Identifiers

PMID41191720
PMCPMC12591269

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.