ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2025
Geographical distribution and spatial autocorrelation of newborns with orofacial clefts: an epidemiological study, Paraná, 2018-2022.
Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the geographical distribution and spatial autocorrelation of cases of orofacial clefts in newborns in Paraná.
methodsThis study employed epidemiological methods using data from the Live Birth Information System for the years 2018-2022. The rates were obtained by dividing the number of live births with orofacial clefts by the total number of births in each year and city, and then multiplying by 1,000. The Global Moran's I was calculated, and spatial autocorrelation was assessed.
resultsDuring the study period, 574 cases of newborns with orofacial clefts were analyzed, distributed across 163 cities in Paraná. The rates ranged from 0.00 to 2.44 cases per 1,000 live births. High-high clusters were present in Londrina, Cornélio Procópio/Bandeirantes, Ivaiporã, Cascavel, Foz do Iguaçu, Francisco Beltrão, Dois Vizinhos, Laranjeiras do Sul/Quedas do Iguaçu, Pato Branco, Guarapuava, and Paranaguá, with rates ranging from 1.10 to 2.44 cases per 1,000 live births.
conclusionThe study highlighted the spatial heterogeneity of newborn cases with orofacial clefts in Paraná, underscoring the need to investigate the causes of orofacial clefts, which will contribute to preventing new cases and enhancing public health actions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.